Anti-Calcium binding protein P22 antibody (ab96203)
Key features and details
- Rabbit polyclonal to Calcium binding protein P22
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-Calcium binding protein P22 antibody
See all Calcium binding protein P22 primary antibodies -
Description
Rabbit polyclonal to Calcium binding protein P22 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Cow -
Immunogen
Synthetic peptide, corresponding to a region within amino acids 47-111 of Human Calcium binding protein P22.
-
Positive control
- HepG2 cells
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96203 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 22 kDa.
|
Notes |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 22 kDa. |
Target
-
Function
Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1. -
Tissue specificity
Ubiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen. -
Sequence similarities
Contains 4 EF-hand domains. -
Post-translational
modificationsBoth N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1. -
Cellular localization
Cytoplasm. - Information by UniProt
-
Database links
- Entrez Gene: 512662 Cow
- Entrez Gene: 11261 Human
- Entrez Gene: 56398 Mouse
- Omim: 606988 Human
- SwissProt: Q3SYS6 Cow
- SwissProt: Q99653 Human
- SwissProt: P61022 Mouse
- Unigene: 406234 Human
see all -
Alternative names
- Calcineurin B homolog antibody
- Calcineurin B homologous protein antibody
- Calcineurin homologous protein antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab96203 has not yet been referenced specifically in any publications.