Key features and details
- Rabbit polyclonal to Calcium binding protein P22 - N-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Calcium binding protein P22 antibody - N-terminal
See all Calcium binding protein P22 primary antibodies
DescriptionRabbit polyclonal to Calcium binding protein P22 - N-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human Calcium binding protein P22 (N terminal).
Database link: Q99653
- HeLa cell extract
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride
PBS without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab196807 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 23 kDa.|
FunctionRequired for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
Tissue specificityUbiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen.
Sequence similaritiesContains 4 EF-hand domains.
modificationsBoth N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.
Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1.
- Information by UniProt
- Calcineurin B homolog antibody
- Calcineurin B homologous protein antibody
- Calcineurin homologous protein antibody
ab196807 has not yet been referenced specifically in any publications.