Key features and details
- Rabbit polyclonal to CALHM1
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-CALHM1 antibody
DescriptionRabbit polyclonal to CALHM1
SpecificityThis antibody is predicted to not crossreact with CALHM2 or CALHM3.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to 17 amino acids near the amino terminus of Human CALHM1 (NP_001001412).
- Rat liver tissue lysate; Rat liver tissue
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106561 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionMay be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
Tissue specificityPredominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells.
Sequence similaritiesBelongs to the FAM26 family.
Cellular localizationCell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum.
- Information by UniProt
- CAHM1_HUMAN antibody
- Calcium homeostasis modulator 1 antibody
- Calcium homeostasis modulator protein 1 antibody
Lane 1 : Anti-CALHM1 antibody (ab106561) at 1 µg/ml
Lane 2 : Anti-CALHM1 antibody (ab106561) at 2 µg/ml
All lanes : Rat liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 38 kDa
Immunohistochemical analysis of CALHM1 in paraffin embedded Rat liver tissue, using ab106561 at 5 µg/ml.
Immunofluorescence of CALHM1 in Rat Liver cells using ab106561 at 20 ug/ml.
ab106561 has not yet been referenced specifically in any publications.