Anti-CALHM1 antibody (ab106561)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-CALHM1 antibody
See all CALHM1 primary antibodies -
Description
Rabbit polyclonal to CALHM1 -
Host species
Rabbit -
Specificity
This antibody is predicted to not crossreact with CALHM2 or CALHM3. -
Tested applications
Suitable for: ICC/IF, WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to 17 amino acids near the amino terminus of Human CALHM1 (NP_001001412).
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Positive control
- Rat liver tissue lysate; Rat liver tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab106561 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 20 µg/ml. | |
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa. | |
| IHC-P | Use a concentration of 5 µg/ml. |
Target
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Function
May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner. -
Tissue specificity
Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells. -
Sequence similarities
Belongs to the FAM26 family. -
Cellular localization
Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum. - Information by UniProt
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Database links
- Entrez Gene: 255022 Human
- Entrez Gene: 546729 Mouse
- Entrez Gene: 499367 Rat
- Omim: 612234 Human
- SwissProt: Q8IU99 Human
- Unigene: 680365 Human
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Alternative names
- CAHM1_HUMAN antibody
- Calcium homeostasis modulator 1 antibody
- Calcium homeostasis modulator protein 1 antibody
see all
Images
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Western blot - Anti-CALHM1 antibody (ab106561)Lane 1 : Anti-CALHM1 antibody (ab106561) at 1 µg/ml
Lane 2 : Anti-CALHM1 antibody (ab106561) at 2 µg/ml
All lanes : Rat liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 38 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CALHM1 antibody (ab106561)Immunohistochemical analysis of CALHM1 in paraffin embedded Rat liver tissue, using ab106561 at 5 µg/ml. -
Immunocytochemistry/ Immunofluorescence - Anti-CALHM1 antibody (ab106561)Immunofluorescence of CALHM1 in Rat Liver cells using ab106561 at 20 ug/ml.
Protocols
Datasheets and documents
References
ab106561 has not yet been referenced specifically in any publications.
