Anti-Calneuron 1 antibody (ab117584)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-Calneuron 1 antibody -
Description
Rabbit polyclonal to Calneuron 1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide conjugated to KLH from the N-terminus of Human Calneuron 1
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Positive control
- Human brain cortex tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab117584 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 24 kDa. | |
| IHC-P | Use a concentration of 2.5 µg/ml. |
Target
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Function
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning. -
Tissue specificity
Brain specific. -
Sequence similarities
Contains 2 EF-hand domains. -
Domain
The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting. -
Cellular localization
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 83698 Human
- Entrez Gene: 140904 Mouse
- Entrez Gene: 363909 Rat
- Omim: 607176 Human
- SwissProt: Q9BXU9 Human
- SwissProt: Q9JJG7 Mouse
- SwissProt: Q06BI3 Rat
- Unigene: 592750 Human
see all -
Alternative names
- CaBP8 antibody
- CABP8_HUMAN antibody
- Calcium binding protein 8 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calneuron 1 antibody (ab117584)Formalin-fixed and paraffin-embedded Human brain cortex tissue labelled with ab117584 at 2.5 µg/ml.
Datasheets and documents
References
This product has been referenced in:
- Kobuke K et al. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma. Hypertension 71:125-133 (2018). Read more (PubMed: 29109191) »
