Overview

  • Product name

    Anti-Calneuron 1 antibody
  • Description

    Rabbit polyclonal to Calneuron 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH from the N-terminus of Human Calneuron 1

  • Positive control

    • Human brain cortex tissue

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab117584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 24 kDa.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • Function

    Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.
  • Tissue specificity

    Brain specific.
  • Sequence similarities

    Contains 2 EF-hand domains.
  • Domain

    The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.
  • Cellular localization

    Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CaBP8 antibody
    • CABP8_HUMAN antibody
    • Calcium binding protein 8 antibody
    • Calcium binding protein antibody
    • Calcium binding protein CABP8 antibody
    • Calcium-binding protein 8 antibody
    • Caln1 antibody
    • Calneuron I antibody
    • Calneuron-1 antibody
    see all

Images

  • Formalin-fixed and paraffin-embedded Human brain cortex tissue labelled with ab117584 at 2.5 µg/ml.

References

This product has been referenced in:

  • Kobuke K  et al. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma. Hypertension 71:125-133 (2018). Read more (PubMed: 29109191) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117584.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up