Anti-Calneuron 1 antibody (ab117584)

Submit a review Submit a question References (1)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calneuron 1 antibody (ab117584)

    Key features and details

    • Rabbit polyclonal to Calneuron 1
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-Calneuron 1 antibody

    • Description

      Rabbit polyclonal to Calneuron 1

    • Host species

      Rabbit

    • Tested applications

      Suitable for: IHC-Pmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse, Rat

    • Immunogen

      Synthetic peptide conjugated to KLH from the N-terminus of Human Calneuron 1

    • Positive control

      • Human brain cortex tissue

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    • Storage buffer

      Preservative: 0.02% Sodium azide
      Constituent: 99% PBS
    • Concentration information loading...

    • Purity

      Immunogen affinity purified

    • Clonality

      Polyclonal

    • Isotype

      IgG

    • Research areas

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab117584 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    Use a concentration of 2.5 µg/ml.
    Notes
    IHC-P
    Use a concentration of 2.5 µg/ml.

    Target

    • Function

      Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.

    • Tissue specificity

      Brain specific.

    • Sequence similarities

      Contains 2 EF-hand domains.

    • Domain

      The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.

    • Cellular localization

      Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • CaBP8 antibody
      • CABP8_HUMAN antibody
      • Calcium binding protein 8 antibody
      • Calcium binding protein antibody
      • Calcium binding protein CABP8 antibody
      • Calcium-binding protein 8 antibody
      • Caln1 antibody
      • Calneuron I antibody
      • Calneuron-1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calneuron 1 antibody (ab117584)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calneuron 1 antibody (ab117584)
      Formalin-fixed and paraffin-embedded Human brain cortex tissue labelled with ab117584 at 2.5 µg/ml.

    References (1)

    Publishing research using ab117584? Please let us know so that we can cite the reference in this datasheet.

    ab117584 has been referenced in 1 publication.

    • Kobuke K  et al. Calneuron 1 Increased Ca2+ in the Endoplasmic Reticulum and Aldosterone Production in Aldosterone-Producing Adenoma. Hypertension 71:125-133 (2018). PubMed: 29109191

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab117584.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com