Key features and details
- Rabbit polyclonal to Calpain 4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Calpain 4 antibody
DescriptionRabbit polyclonal to Calpain 4
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide within Human Calpain 4 aa 50-150 (internal sequence). The exact sequence is proprietary.
Database link: P04632
- Human breast tissue
This product is FOR RESEARCH USE ONLY. For commercial use, please contact firstname.lastname@example.org.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab93959 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
RelevanceCalpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes.Calpain 4 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
Cellular localizationCytoplasm. Cell membrane. Note: Translocates to the plasma membrane upon calcium binding
- 30K antibody
- Calcium activated neutral proteinase antibody
- Calcium activated neutral proteinase small subunit antibody
ab93959 has been referenced in 2 publications.
- Cai JJ et al. Increased expression of Capn4 is associated with the malignancy of human glioma. CNS Neurosci Ther 20:521-7 (2014). PubMed: 24628706
- Liu T et al. Calpastatin is regulated by protein never in mitosis gene A interacting-1 (PIN1) in endothelial cells. Biochem Biophys Res Commun 414:581-6 (2011). PubMed: 21982763