Overview

  • Product name

    Anti-Calpain 7 antibody [2107C3a]
  • Description

    Mouse monoclonal [2107C3a] to Calpain 7
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Dot blotmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab51293 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 93 kDa.
Dot blot Use at an assay dependent dilution.

Target

  • Relevance

    Calpain proteinases are defined currently as papain-like neutral proteases that are calcium activated. Calpains 1 and 2 are composed of a large subunit, which is proteolytically active, and a small subunit (also called calpain 4), or enhancer protein, that is not proteolytically active. The other calpain proteins identified to date (Calpain 5, 6, 8, 9, 10, 11, 12, 13, 14, 15) are not known to require a small subunit. Domains in the large subunit include the amino terminal domain-I, the proteinase domain-II, domain-III, and the EF-hand domain-IV (domain-T in calpains 5 & 6, domain-N for calpain 7). Calpain 7 domain-N does not have the standard calpain EF hand domain for binding calcium, making it unclear whether it is calcium regulated. In place of the EF hand calcium-binding domain IV, Calpain 7 has a sequence most closely resembling domain-III, with unknown function. Calpain 7 is widely distributed, found in most tissues analyzed.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • Calpain like protease antibody
    • Calpain7 antibody
    • CAPN 7 antibody
    • Homolog of Aspergillus Nidulans PALB antibody
    • PALBH antibody
    see all

Images

  • Anti-Calpain 7 antibody [2107C3a] (ab51293) + Immunizing peptide

    Predicted band size: 93 kDa

References

ab51293 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab51293.
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