Overview

  • Product name

    Calpeptin, cell-permeable calpain inhibitor
  • Description

    Potent, cell-permeable calpain inhibitor
  • Biological description

    Potent, cell-permeable calpain inhibitor, a Ca2+-dependent protease. Ki values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier.
  • Purity

    > 98%
  • CAS Number

    117591-20-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Smith AW  et al. Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis. Invest Ophthalmol Vis Sci 52:4935-41 (2011). Read more (PubMed: 21613375) »
  • Rodríguez-Agudo D  et al. Rat histidine decarboxylase is a substrate for m-calpain in vitro. Biochem Biophys Res Commun 271:777-81 (2000). Read more (PubMed: 10814538) »
  • Tsujinaka T  et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun 153:1201-8 (1988). Read more (PubMed: 2839170) »
See all 4 Publications for this product

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