Overview

  • Product name

  • Description

    Rabbit polyclonal to CAMK1D
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous levels of total CAMK1D protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Fusion protein corresponding to Human CAMK1D (internal sequence). The identity of the protein fusion partner is GST
    Database link: Q8IU85

  • Positive control

    • Human thyroid cancer tissue; Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.

Target

  • Function

    Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
  • Tissue specificity

    Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Domain

    The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • Cellular localization

    Cytoplasm. Nucleus. Predominantly cytoplasmic (Probable). Also nuclear upon activation.
  • Information by UniProt
  • Database links

  • Alternative names

    • A630059D12Rik antibody
    • Calcium/calmodulin dependent protein kinase ID antibody
    • Calcium/calmodulin dependent protein kinase type 1D antibody
    • Calcium/calmodulin-dependent protein kinase I-delta antibody
    • Calcium/calmodulin-dependent protein kinase type 1D antibody
    • CaM K1 antibody
    • CaM KI delta antibody
    • CaM kinase I delta antibody
    • CaM kinase ID antibody
    • CaM-KI delta antibody
    • CAMK 1D antibody
    • CAMK1D antibody
    • CaMKI delta antibody
    • CamKI like protein kinase antibody
    • CamKI-like protein kinase antibody
    • CaMKID antibody
    • CKLiK antibody
    • E030025C11Rik antibody
    • KCC1D_HUMAN antibody
    • OTTHUMP00000019119 antibody
    • OTTHUMP00000019120 antibody
    • OTTHUMP00000045030 antibody
    • RP11 462F15.1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded human brain tissue labeling CAMK1D with ab198165 at a 1/50 dilution.

  • Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue labeling CAMK1D with ab198165 at a 1/50 dilution.

References

ab198165 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198165.
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