Overview

  • Product name
    CaMKII peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      ALRRQETVDAL
    • Additional sequence information
      Peptide sequence based on the autophosphorylation site (amino acid 283-290) on CaMKII alpha.

Specifications

Our Abpromise guarantee covers the use of ab188554 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    Functional Studies

  • Form
    Lyophilised
  • Additional notes

    ab188554 (CaMKII peptide) can be utilized as a substrate for the following active protein kinases:

     

    ab51398 (Active mouse CaMKI full length protein)
    ab60891 (Active human PNCK full length protein)
    ab60898 (Active human CAMK 1D beta full length protein)
    ab51400 (Active human CaMKI gamma protein fragment)
    ab60899 (Active human CaMKII alpha full length protein)
    ab84552 (Active human CaMKII delta full length protein)
    ab63189 (Active human CamKII gamma protein fragment)
    ab60756 (Human CAMKIV full length protein)
    ab101777 (Active human DCAMKL1 full length protein)

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

  • Reconstitution
    Dilute peptide in distilled water to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.

General Info

  • Alternative names
    • Calcium/calmodulin dependent protein kinase II alpha
    • Calcium/calmodulin dependent protein kinase II beta
    • Calcium/calmodulin dependent protein kinase II delta
    • Calcium/calmodulin dependent protein kinase II gamma
    • Calcium/calmodulin-dependent protein kinase type II subunit alpha
    • CaM kinase II
    • CaM kinase II alpha
    • CaM kinase II beta
    • CaM kinase II delta
    • CaM kinase II gamma
    • CaM kinase II subunit alpha
    • CaMK-II subunit alpha
    • CAMK2
    • Camk2a
    • CAMK2B
    • CAMK2D
    • CAMK2G
    • CAMKA
    • KCC2A_HUMAN
    see all
  • Function
    CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • Cellular localization
    Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse. Postsynaptic lipid rafts.
  • Information by UniProt

References

ab188554 has not yet been referenced specifically in any publications.

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