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Targeting the PD-1/PD-L1 axis has been a successful therapeutic strategy against several tumor types. The following table outlines tools to study the PD-1 and PD-L1 pathway:
|PBS only formulations||BSA & Azide free||BSA & Azide free|
|ELISA kits||Mouse PD-1 SimpleStep ELISA® kit||Human PD-L1 [28-8] SimpleStep ELISA® kit|
SimpleStep ELISA kits are one-step assays for quantification of your target protein.
|PD-1||90min||Mouse||Colorimetric||21 pg/mL||125–8,000 pg/mL|
|PD-L1 [28-8]||90min||Human||Colorimetric||3.81 pg/mL||21.9–1,400 pg/mL|
The panel above shows interpolated concentrations of native PD1 in mouse EL-4 cell extract samples based on a 180 µg/mL extract load (left). Interpolated concentrations of native PD-L1 in human Jurkat stimulated with LPS and IFN-gamma, placenta, and thyroid based on a 1,000 µg/mL extract load (right).
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