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  1. Link

    cannabinoid-receptor-i-antibody-ab167366.pdf

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Neuroscience Neurotransmission Receptors / Channels GPCR Cannabinoid Receptor
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Anti-Cannabinoid Receptor I antibody (ab167366)

  • Datasheet
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Western blot - Anti-Cannabinoid Receptor I antibody (ab167366)

    Key features and details

    • Mouse polyclonal to Cannabinoid Receptor I
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

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    Recombinant Human Cannabinoid Receptor I protein (ab158150)
    Secondary
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    Goat Anti-Mouse IgG H&L (HRP) (ab205719)
    Primary
    Product image
    Anti-Cannabinoid Receptor II antibody (ab3561)

    View more associated products

    Overview

    • Product name

      Anti-Cannabinoid Receptor I antibody
      See all Cannabinoid Receptor I primary antibodies
    • Description

      Mouse polyclonal to Cannabinoid Receptor I
    • Host species

      Mouse
    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Human
    • Immunogen

      Recombinant full length protein within Human Cannabinoid Receptor I aa 1-500. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • Positive control

      • Cannabinoid Receptor I transfected 293T cell line lysate.
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
    • Storage buffer

      pH: 7.4
      Constituent: 99% PBS
    • Concentration information loading...
    • Purity

      Protein A purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • Cannabinoid Receptor
      • Cardiovascular
      • Lipids / Lipoproteins
      • Lipid Metabolism
      • Cholesterol Metabolism
      • Signal Transduction
      • Metabolism
      • Drug metabolism
      • Cardiovascular
      • Atherosclerosis
      • Lipoprotein metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Cholesterol Metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Lipoprotein metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Drug metabolism
      • Metabolism
      • Types of disease
      • Heart disease
      • Neuroscience
      • Processes

    Associated products

    • Compatible Secondaries

      • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
      • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
    • Isotype control

      • Mouse IgG - Isotype Control (ab37355)
    • Recombinant Protein

      • Recombinant Human Cannabinoid Receptor I protein (ab158150)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab167366 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa.
    Notes
    WB
    Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa.

    Target

    • Function

      Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
    • Tissue specificity

      Widely expressed.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P21554 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 1268 Human
      • Omim: 114610 Human
      • SwissProt: P21554 Human
      • Unigene: 709067 Human
      • Unigene: 75110 Human
      • Alternative names

        • CANN6 antibody
        • Cannabinoid receptor 1 antibody
        • CB-R antibody
        • CB1 antibody
        • CB1A antibody
        • CB1K5 antibody
        • CB1R antibody
        • Central cannabinoid receptor antibody
        • CNR antibody
        • CNR1 antibody
        • CNR1_HUMAN antibody
        • OTTHUMP00000016838 antibody
        • OTTHUMP00000214579 antibody
        see all

      Images

      • Western blot - Anti-Cannabinoid Receptor I antibody (ab167366)
        Western blot - Anti-Cannabinoid Receptor I antibody (ab167366)
        All lanes : Anti-Cannabinoid Receptor I antibody (ab167366) at 1 µg/ml

        Lane 1 : Cannabinoid Receptor I transfected 293T cell line lysate
        Lane 2 : Non-transfected 293T cell line lysate

        Lysates/proteins at 15 µl per lane.

        Secondary
        All lanes : Goat anti-Mouse IgG HRP at 1/2500 dilution

        Predicted band size: 53 kDa

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet download

        Download

      References (1)

      Publishing research using ab167366? Please let us know so that we can cite the reference in this datasheet.

      ab167366 has been referenced in 1 publication.

      • Zheng Y  et al. Electroacupuncture alleviates morphine-induced hyperalgesia by regulating spinal CB1 receptors and ERK1/2 activity. Mol Med Rep 20:1113-1120 (2019). PubMed: 31173210

      Customer reviews and Q&As

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      There are currently no Customer reviews or Questions for ab167366.
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