Cannabinoid Receptor I peptide (ab50542)
Key features and details
- Suitable for: Blocking
Description
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Product name
Cannabinoid Receptor I peptide
See all Cannabinoid Receptor I proteins and peptides -
Animal free
No -
Nature
Synthetic
Associated products
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Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab50542 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking - Blocking peptide for Anti-Cannabinoid Receptor I antibody (ab23703)
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline
General Info
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Alternative names
- CANN6
- Cannabinoid receptor 1
- CB-R
see all -
Function
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. -
Tissue specificity
Widely expressed. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (7)
ab50542 has been referenced in 7 publications.
- Nielsen JE et al. Characterisation and localisation of the endocannabinoid system components in the adult human testis. Sci Rep 9:12866 (2019). PubMed: 31537814
- Jang JH et al. Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and inflammatory pain in mice. Sci Rep 8:707 (2018). PubMed: 29335480
- Gustafsson SB et al. High Tumour Cannabinoid CB(1) Receptor Immunoreactivity Negatively Impacts Disease-Specific Survival in Stage II Microsatellite Stable Colorectal Cancer. PLoS One 6:e23003 (2011). PubMed: 21901119
- Björklund E et al. Increased Expression of Cannabinoid CB(1) Receptors in Achilles Tendinosis. PLoS One 6:e24731 (2011). Blocking . PubMed: 21931835
- Zurolo E et al. CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies. Neuroscience 170:28-41 (2010). IHC-P, Blocking . PubMed: 20621164
- Tyagi V et al. Differential expression of functional cannabinoid receptors in human bladder detrusor and urothelium. J Urol 181:1932-8 (2009). WB, Blocking . PubMed: 19237176
- Horne AW et al. CB1 expression is attenuated in Fallopian tube and decidua of women with ectopic pregnancy. PLoS ONE 3:e3969 (2008). Blocking, IHC-Fr . PubMed: 19093002