Overview

Description

  • Nature
    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab50542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Cannabinoid Receptor I antibody (ab23703)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline, pH 7.4

General Info

  • Alternative names
    • CANN6
    • Cannabinoid receptor 1
    • CB-R
    • CB1
    • CB1A
    • CB1K5
    • CB1R
    • Central cannabinoid receptor
    • CNR
    • CNR1
    • CNR1_HUMAN
    • OTTHUMP00000016838
    • OTTHUMP00000214579
    see all
  • Function
    Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
  • Tissue specificity
    Widely expressed.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

This product has been referenced in:
  • Jang JH  et al. Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and inflammatory pain in mice. Sci Rep 8:707 (2018). Read more (PubMed: 29335480) »
  • Gustafsson SB  et al. High Tumour Cannabinoid CB(1) Receptor Immunoreactivity Negatively Impacts Disease-Specific Survival in Stage II Microsatellite Stable Colorectal Cancer. PLoS One 6:e23003 (2011). Read more (PubMed: 21901119) »

See all 6 Publications for this product

Publishing research using ab50542? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Submit a review Submit a question

2 reviews or Q&A

10
Votes: Highest First

Inquiry: Hello. I have such question: Is this peptide (human cannabinoid receptor I peptide) suitable for study kinetics of binding this peptide with chemical agent (small molecule)? If not, what can you advise? I plan to use Biacore apparatus .

Thank you for your enquiry.

I can confirm that this peptide has been designed as an immunogen for Cannabinoid Receptor I antibody ab23703. It can be used as a blocking peptide with this antibody. I am sorry wee have no data to show that the ...

Read More

What is the molecular weight of this peptide?

This 12 amino acid peptide immunogen has a molecular weight of 1,211.3 Da.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up