Recombinant Anti-Cannabinoid Receptor I (phospho S316) antibody [EPR2223(N)] - BSA and Azide free (ab243927)


  • Product name

    Anti-Cannabinoid Receptor I (phospho S316) antibody [EPR2223(N)] - BSA and Azide free
    See all Cannabinoid Receptor I primary antibodies
  • Description

    Rabbit monoclonal [EPR2223(N)] to Cannabinoid Receptor I (phospho S316) - BSA and Azide free
  • Host species

  • Tested applications

    Suitable for: WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Cannabinoid Receptor I aa 300-400 (phospho S316). The exact sequence is proprietary.
    Database link: P21554

  • Positive control

    • Human fetal brain lysate; SH-SY5Y cells.
  • General notes

    Ab243927 is the carrier-free version of ab186428. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.


    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab243927 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab243927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 46, 53 kDa (predicted molecular weight: 53 kDa).
Flow Cyt Use at an assay dependent concentration.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.


  • Function

    Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CANN6 antibody
    • Cannabinoid receptor 1 antibody
    • CB-R antibody
    • CB1 antibody
    • CB1A antibody
    • CB1K5 antibody
    • CB1R antibody
    • Central cannabinoid receptor antibody
    • CNR antibody
    • CNR1 antibody
    • CNR1_HUMAN antibody
    • OTTHUMP00000016838 antibody
    • OTTHUMP00000214579 antibody
    see all


  • Flow cytometry analysis of Cannabinoid Receptor I (phospho S316) expression in 2% paraformaldehyde-fixed SH-SY5Y cells using ab186428 at 1/200 dilution (red) or a rabbit IgG isotype control (green), SH-SY5Y cells preincubated with Cannabinoid Receptor I (phospho S316) peptide (blue) or non-phosopho Cannabinoid Receptor I (phospho S316) peptide (orange). FITC-conjugated goat anti-rabbit IgG (1/150 dilution) was used as the secondary antibody.

    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab186428)


ab243927 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab243927.
Please use the links above to contact us or submit feedback about this product.

For licensing inquiries, please contact

Sign up