Overview

  • Product name

    Anti-CAPRIN2 antibody
  • Description

    Rabbit polyclonal to CAPRIN2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen sequence: TPKPRENNVE SQKHSLTSQS QISPKSWGVA TASLIPNDQL LPRKLNTEPK DVPKPVHQPV GSSSTLPKDP VLRKEKLQDL MTQIQGT, corresponding to internal sequence amino acids 544-630 of Human CAPRIN2.

  • Positive control

    • Human hippocampus tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis.
  • Tissue specificity

    Detected in all tissues tested with highest levels of expression in brain and spleen.
  • Sequence similarities

    Belongs to the caprin family.
    Contains 1 C1q domain.
  • Developmental stage

    Expression is highly regulated during erythroid development with increased expression at the stage of differentiation associated with the onset of global nuclear condensation and reduced cell proliferation.
  • Cellular localization

    Cytoplasm; Mitochondrion. Colocalizes with aggregated mitochondria and Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • C1q domain-containing protein 1 antibody
    • C1QDC1 antibody
    • CAPR2_HUMAN antibody
    • Caprin family member 2 antibody
    • Caprin-2 antibody
    • caprin2 antibody
    • Cytoplasmic activation/proliferation-associated protein 2 antibody
    • EEG 1 antibody
    • EEG1 antibody
    • Gastric cancer multidrug resistance-associated protein antibody
    • KIAA1873 antibody
    • Protein EEG-1 antibody
    • RNA granule protein 140 antibody
    • RNG140 antibody
    see all

Images

  • ab122583, at 1/20 dilution, staining CAPRIN2 in paraffin-embedded Human hippocampus tissue by Immunohistochemistry.

References

ab122583 has not yet been referenced specifically in any publications.

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