Overview

  • Product name

  • Description

    Rabbit polyclonal to CAPZA1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within internal sequence amino acids 66-267 of Human CAPZA1 (P52907).

  • Positive control

    • 293T, A431, Jurkat and Raji whole cell lysates.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 1% BSA, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab125972 is purified by antigen-affinity chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab125972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

Target

  • Function

    F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
  • Sequence similarities

    Belongs to the F-actin-capping protein alpha subunit family.
  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cap Z antibody
    • Cappa 1 antibody
    • Cappa1 antibody
    • Capping protein (actin filament) muscle Z line alpha 1 antibody
    • Capping protein alpha 1 antibody
    • Capping protein muscle Z line alpha 1 antibody
    • CapZ alpha 1 antibody
    • CapZ alpha-1 antibody
    • CAPZ antibody
    • CAPZA 1 antibody
    • Capza1 antibody
    • CAZ 1 antibody
    • CAZ1 antibody
    • CAZA1_HUMAN antibody
    • F actin capping protein alpha 1 subunit antibody
    • F-actin-capping protein subunit alpha-1 antibody
    see all

Images

  • All lanes : Anti-CAPZA1 antibody (ab125972) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : Jurkat whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 33 kDa



    12% SDS PAGE

References

This product has been referenced in:

  • Riedl I  et al. Association of the ACTN3 R577X polymorphism with glucose tolerance and gene expression of sarcomeric proteins in human skeletal muscle. Physiol Rep 3:N/A (2015). Read more (PubMed: 25780092) »
See 1 Publication for this product

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