FITC Anti-Carbonic Anhydrase 12/CA12 antibody [11] (ab275576)
Key features and details
- FITC Mouse monoclonal [11] to Carbonic Anhydrase 12/CA12
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-Carbonic Anhydrase 12/CA12 antibody [11]
See all Carbonic Anhydrase 12/CA12 primary antibodies -
Description
FITC Mouse monoclonal [11] to Carbonic Anhydrase 12/CA12 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment (His-tag) corresponding to Human Carbonic Anhydrase 12/CA12 aa 1-300 (extracellular).
Database link: O43570 -
Positive control
- Flow Cyt: MCF7 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
11 -
Isotype
IgG1 -
Research areas
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab275576 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
5 µl/Test |
Notes |
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Flow Cyt
Use at an assay dependent concentration. 5 µl/Test |
Target
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Function
Reversible hydration of carbon dioxide. -
Tissue specificity
Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. -
Involvement in disease
Defects in CA12 are the cause of hyperchlorhidrosis isolated (HCHLH) [MIM:143860]. HCHLH is a disorder characterized by excessive sweating and increased sweat chloride levels. Affected individuals suffer from episodes of hyponatremic dehydration and report increased amounts of visible salt precipitates in sweat. -
Sequence similarities
Belongs to the alpha-carbonic anhydrase family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 771 Human
- Omim: 603263 Human
- SwissProt: O43570 Human
- Unigene: 210995 Human
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Alternative names
- CA 12 antibody
- CA XII antibody
- CA-XII antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab275576 has not yet been referenced specifically in any publications.