Key features and details
- Antitumor agent; blocks DNA replication and transcription. Cisplatin analog.
- CAS Number: 41575-94-4
- Purity: > 99%
- Soluble in water to 25 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameCarboplatin, Antitumor agent
DescriptionAntitumor agent; blocks DNA replication and transcription. Cisplatin analog.
Antitumor agent. Forms platinum-DNA adducts blocking DNA replication and transcription. Displays lower nephrotoxicity than analog, cisplatin (ab141398). Active in vivo.
Chemical namecis-Diamine(1,1-cyclobutanedicarboxylato)platinum (II)
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 25 mM and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120828 has been referenced in 1 publication.
- Hastings JF et al. Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma. Elife 9:N/A (2020). PubMed: 32513387