Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate (ab145286)

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Overview

  • Product name
    Carboxy-DCFDA N-succinimidyl ester, Fluorogenic esterase substrate
  • Description
    Cell-permeable, fluorogenic esterase substrate
  • Biological description

    Cell-permeable, fluorogenic esterase substrate. Becomes hydrolyzed intracellularly to green fluorophore DCFA (ab145439) and covalently bonds to proteins.

  • Purity
    > 96%
  • CAS Number
    147265-60-9
  • Chemical structure
    Chemical Structure

Properties

  • Excitation
    495nm
  • Emission
    529nm
  • Chemical name
    5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester
  • Molecular weight
    626.35
  • Molecular formula
    C29H17Cl2NO11
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Skarabahatava AS  et al. Plasma and mitochondrial membrane perturbation induced by aluminum in human peripheral blood lymphocytes. J Trace Elem Med Biol 31:37-44 (2015). Read more (PubMed: 26004890) »
  • Aljanadi O  et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol : (2015). Read more (PubMed: 26013059) »
  • Deng R  et al. Oxidative stress markers induced by hyperosmolarity in primary human corneal epithelial cells. PLoS One 10:e0126561 (2015). Read more (PubMed: 26024535) »
See all 2 Publications for this product

Publishing research using ab145286? Please let us know so that we can cite the reference in this datasheet.

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