Anti-Carboxymethyl Lysine antibody (ab27683)
Key features and details
- Goat polyclonal to Carboxymethyl Lysine
- Suitable for: WB, ELISA
- Reacts with: Species independent
- Isotype: IgG
Overview
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Product name
Anti-Carboxymethyl Lysine antibody
See all Carboxymethyl Lysine primary antibodies -
Description
Goat polyclonal to Carboxymethyl Lysine -
Host species
Goat -
Specificity
This antibody specifically binds to Carboxy Methyl Lysine modified proteins. -
Tested applications
Suitable for: WB, ELISAmore details -
Species reactivity
Reacts with: Species independent -
Immunogen
Carboxy methyl Lysine conjugated to KLH.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0292% EDTA, 0.435% Sodium chloride, 30% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
purified by CML-protein-SepharoseTM affinity column -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab27683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2500 - 1/20000.
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ELISA |
1/2500 - 1/20000.
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Notes |
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WB
1/2500 - 1/20000. |
ELISA
1/2500 - 1/20000. |
Target
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Relevance
N epsilon carboxymethyl lysine (CML or Carboxymethyl Lysine) is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy. -
Alternative names
- CML antibody
- N Epsilon (Carboxymethyl) Lysine antibody
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab27683 has not yet been referenced specifically in any publications.