Recombinant Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7858] to Carboxypeptidase B2
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Carboxypeptidase B2 antibody [EPR7858]
See all Carboxypeptidase B2 primary antibodies -
Description
Rabbit monoclonal [EPR7858] to Carboxypeptidase B2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human platelet and plasma lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Dissociation constant (KD)
KD = 3.67 x 10 -11 M Learn more about KD -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR7858 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab133679 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 48 kDa. |
Target
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Function
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. -
Tissue specificity
Plasma; synthesized in the liver. -
Sequence similarities
Belongs to the peptidase M14 family. -
Post-translational
modificationsN-glycosylated. N-glycan at Asn-108: Hex5HexNAc4. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1361 Human
- Entrez Gene: 56373 Mouse
- Entrez Gene: 113936 Rat
- Omim: 603101 Human
- SwissProt: Q96IY4 Human
- SwissProt: Q9JHH6 Mouse
- SwissProt: Q9EQV9 Rat
- Unigene: 512937 Human
see all -
Alternative names
- 1110032P04Rik antibody
- 4930405E17Rik antibody
- bA139H14.2 antibody
see all
Images
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All lanes : Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679) at 1/1000 dilution
Lane 1 : Human platelet lysate
Lane 2 : Human plasma lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution
Predicted band size: 48 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab133679 has not yet been referenced specifically in any publications.