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    carcino-embryonic-antigen-cea-antibody-ab131070.pdf

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Tags & Cell Markers Cell Type Markers Tumor Associated
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Anti-Carcino Embryonic Antigen CEA antibody (ab131070)

  • Datasheet
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Key features and details

  • Rabbit polyclonal to Carcino Embryonic Antigen CEA
  • Reacts with: Human
  • Isotype: IgG

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Recombinant Human Carcino Embryonic Antigen CEA protein (ab158095)
Secondary
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Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-Carcino Embryonic Antigen CEA antibody
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description

    Rabbit polyclonal to Carcino Embryonic Antigen CEA
  • Host species

    Rabbit
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Insect cells-derived recombinant full length Human CEACAM5.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.025% Sodium azide
    Constituents: 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Tags & Cell Markers
    • Cell Type Markers
    • Tumor Associated
    • Stem Cells
    • Mesenchymal Stem Cells
    • Surface Molecules
    • Cancer
    • Tumor immunology
    • Tumor-associated antigens
    • Cancer
    • Tumor biomarkers
    • Tumor antigens
    • Microbiology
    • Protein
    • Human Protein
    • Receptor

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Carcino Embryonic Antigen CEA protein (ab158095)

Target

  • Function

    Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • Tissue specificity

    Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • Post-translational
    modifications

    Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession P06731 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1048 Human
    • Omim: 114890 Human
    • SwissProt: P06731 Human
    • Unigene: 709196 Human
    • Alternative names

      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Protocols

    • Western blot protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (3)

    Publishing research using ab131070? Please let us know so that we can cite the reference in this datasheet.

    ab131070 has been referenced in 3 publications.

    • Bai Y  et al. Combined detection of estrogen and tumor markers is an important reference factor in the diagnosis and prognosis of lung cancer. J Cell Biochem 120:105-114 (2019). PubMed: 30216488
    • Duclos GE  et al. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Sci Adv 5:eaaw3413 (2019). PubMed: 31844660
    • Chu H  et al. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem 293:11709-11726 (2018). PubMed: 29887526

    Customer reviews and Q&As

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