Overview

  • Product name
    Anti-Carcino Embryonic Antigen CEA antibody
    See all Carcino Embryonic Antigen CEA primary antibodies
  • Description
    Rabbit polyclonal to Carcino Embryonic Antigen CEA
  • Host species
    Rabbit
  • Specificity
    Recognizes human CEA and CEA like proteins such as non specific crossreacting antigen (NCA), NCA2, and biliary glycoprotein (BGP1). Has been absorbed with plasma proteins and blood group antigens A and B.
  • Tested applications
    Suitable for: IP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Does not react with: Dog
  • Immunogen

    Human Carcino Embryonic Antigen CEA isolated from hepatic metastasis of colon adenocarcinoma

  • Positive control
    • LS174T cells or colon carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab33562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
WB 1/200. Predicted molecular weight: 77 kDa.
IHC-P 1/500 - 1/1000. Antigen retrieval is not essential but may optimise staining.

Target

  • Function
    Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
  • Tissue specificity
    Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains.
  • Post-translational
    modifications
    Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Carcinoembryonic antigen antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
    • CD66e antibody
    • CEA antibody
    • Ceacam5 antibody
    • CEAM5_HUMAN antibody
    • DKFZp781M2392 antibody
    • Meconium antigen 100 antibody
    • OTTHUMP00000199032 antibody
    • OTTHUMP00000199033 antibody
    • OTTHUMP00000199034 antibody
    see all

References

This product has been referenced in:
See all 3 Publications for this product

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (Frozen sections)
Sample
Rat Tissue sections (liver)
Specification
liver
Fixative
Acetone
Permeabilization
No

Dr. Krause

Verified customer

Submitted Feb 08 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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