PE Anti-CEACAM5 antibody [CB30] (ab42796)
Key features and details
- PE Mouse monoclonal [CB30] to CEACAM5
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
PE Anti-CEACAM5 antibody [CB30]
See all CEACAM5 primary antibodies -
Description
PE Mouse monoclonal [CB30] to CEACAM5 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length native protein (purified) corresponding to Human CEACAM5.
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General notes
ab42796 is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. It is found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.5% BSA -
Concentration information loading...
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Purification notes
ab42796 is a purified fraction from size exclusion chromatography. -
Primary antibody notes
ab42796 is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. It is found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. -
Clonality
Monoclonal -
Clone number
CB30 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab42796 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt |
Use at an assay dependent concentration.
10 ul is sufficient to label 0.1 - 1x10^6 leucocytes in 100 ul. ab91357 - Mouse monoclonal IgG1 is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. 10 ul is sufficient to label 0.1 - 1x10^6 leucocytes in 100 ul. ab91357 - Mouse monoclonal IgG1 is suitable for use as an isotype control with this antibody. |
Target
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Function
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. -
Tissue specificity
Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. -
Sequence similarities
Belongs to the immunoglobulin superfamily. CEA family.
Contains 7 Ig-like (immunoglobulin-like) domains. -
Post-translational
modificationsComplex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1048 Human
- Omim: 114890 Human
- SwissProt: P06731 Human
- Unigene: 709196 Human
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Alternative names
- Carcinoembryonic antigen antibody
- Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
- CD66e antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab42796 has been referenced in 2 publications.
- McNeil NE et al. Novel mouse model recapitulates genome and transcriptome alterations in human colorectal carcinomas. Genes Chromosomes Cancer 56:199-213 (2017). PubMed: 27750367
- Ray S et al. Establishment of human ultra-low passage colorectal cancer cell lines using spheroids from fresh surgical specimens suitable for in vitro and in vivo studies. J Cancer 3:196-206 (2012). Flow Cyt . PubMed: 22606209