Overview

  • Product name

  • Description

    Mouse polyclonal to CARD9
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length Human CARD9 (amino acids 1-492; AAH08877.1).

  • Positive control

    • CARD9 transfected 293T cell lysate; HeLa cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab169623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • Function

    Activates NF-kappa-B via BCL10.
  • Tissue specificity

    Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
  • Involvement in disease

    Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
  • Sequence similarities

    Contains 1 CARD domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CANDF2 antibody
    • CARD9 antibody
    • CARD9_HUMAN antibody
    • Caspase recruitment domain family member 9 antibody
    • Caspase recruitment domain-containing protein 9 antibody
    • hCARD9 antibody
    see all

Images

  • All lanes : Anti-CARD9 antibody (ab169623) at 1 µg/ml

    Lane 1 : CARD9 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Developed using the ECL technique.

    Predicted band size: 56 kDa

  • Immunofluorescent analysis of HeLa cells labeling CARD9 with ab169623 at 10 µg/ml.

References

ab169623 has not yet been referenced specifically in any publications.

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