Anti-CARD9 antibody (ab169623)

Product name

Anti-CARD9 antibody
See all CARD9 primary antibodies
Description

Mouse polyclonal to CARD9
Host species

Mouse
Tested applications

Suitable for: WB, ICC/IFmore details
Species reactivity

Reacts with: Human
Immunogen

Full length Human CARD9 (amino acids 1-492; AAH08877.1).

Run BLAST with Run BLAST with
Positive control
- CARD9 transfected 293T cell lysate; HeLa cells.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage buffer

pH: 7.20
Constituent: 99% PBS
Concentration information loading...
Purity

Protein A purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab169623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
WB		Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa.
ICC/IF		Use a concentration of 10 µg/ml.

Function

Activates NF-kappa-B via BCL10.
Tissue specificity

Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Involvement in disease

Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
Sequence similarities

Contains 1 CARD domain.
Cellular localization

Cytoplasm.
Target information above from: UniProt accession Q9H257 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 64170 Human
- Omim: 607212 Human
- SwissProt: Q9H257 Human
- Unigene: 694071 Human
Alternative names
- CANDF2 antibody
- CARD9 antibody
- CARD9_HUMAN antibody
- Caspase recruitment domain family member 9 antibody
- Caspase recruitment domain-containing protein 9 antibody
- hCARD9 antibody
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Western blot - Anti-CARD9 antibody (ab169623)

All lanes : Anti-CARD9 antibody (ab169623) at 1 µg/ml

Lane 1 : CARD9 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate

Lysates/proteins at 15 µl per lane.

Developed using the ECL technique.

Predicted band size: 56 kDa
Immunocytochemistry/ Immunofluorescence - Anti-CARD9 antibody (ab169623)

Immunofluorescent analysis of HeLa cells labeling CARD9 with ab169623 at 10 µg/ml.

ab169623 has not yet been referenced specifically in any publications.

Publishing research using ab169623? Please let us know so that we can cite the reference in this datasheet.

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