Key features and details
- Mouse polyclonal to CARD9
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.4
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab169623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa.|
|ICC/IF||Use a concentration of 10 µg/ml.|
FunctionActivates NF-kappa-B via BCL10.
Tissue specificityHighly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Involvement in diseaseDefects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
Sequence similaritiesContains 1 CARD domain.
- Information by UniProt
- CANDF2 antibody
- CARD9 antibody
- CARD9_HUMAN antibody
All lanes : Anti-CARD9 antibody (ab169623) at 1 µg/ml
Lane 1 : CARD9 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 56 kDa
Immunofluorescent analysis of HeLa cells labeling CARD9 with ab169623 at 10 µg/ml.
ab169623 has not yet been referenced specifically in any publications.