Overview

  • Product name

  • Description

    Rabbit polyclonal to CARD9
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Rat, Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to N terminal residues of human CARD9.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab55950 was purified by antigen specific affinity chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab55950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 62 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

Target

  • Function

    Activates NF-kappa-B via BCL10.
  • Tissue specificity

    Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
  • Involvement in disease

    Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2) [MIM:212050]. Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis.
  • Sequence similarities

    Contains 1 CARD domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CANDF2 antibody
    • CARD9 antibody
    • CARD9_HUMAN antibody
    • Caspase recruitment domain family member 9 antibody
    • Caspase recruitment domain-containing protein 9 antibody
    • hCARD9 antibody
    see all

References

This product has been referenced in:

  • Freed JK & Greene AS Proteomic analysis of shear stress-mediated protection from TNF-alpha in endothelial cells. Microcirculation 17:259-70 (2010). Read more (PubMed: 20536739) »
See 1 Publication for this product

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