Anti-Cardiac Troponin I antibody (ab47003)

Rabbit polyclonal Cardiac Troponin I antibody. Validated in WB, ELISA, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human, Pig. Cited in 54 publication(s). Independently reviewed in 14 review(s).

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ab47003 has been referenced in 58 publications.

  • Onwuli DO  et al. The inhibitory subunit of cardiac troponin (cTnI) is modified by arginine methylation in the human heart. Int J Cardiol N/A:N/A (2019). PubMed: 30772011
  • Suwa Y  et al. Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a PKD1 Frameshift Mutation. Int Heart J 60:220-225 (2019). PubMed: 30464138
  • Ferreira JCB  et al. A selective inhibitor of mitofusin 1-ßIIPKC association improves heart failure outcome in rats. Nat Commun 10:329 (2019). PubMed: 30659190
  • Wang X  et al. GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway. Life Sci 226:22-32 (2019). PubMed: 30905784
  • Hakuno D  et al. Hepatokine a1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Sci Rep 8:16749 (2018). PubMed: 30425314
  • Ferguson SW  et al. The microRNA regulatory landscape of MSC-derived exosomes: a systems view. Sci Rep 8:1419 (2018). PubMed: 29362496
  • Wang Z  et al. Imaging transparent intact cardiac tissue with single-cell resolution. Biomed Opt Express 9:423-436 (2018). PubMed: 29552383
  • Schneider C  et al. The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients. Sci Rep 8:5295 (2018). PubMed: 29593308
  • Khodayari Bavil A & Kim J A capillary flow-driven microfluidic system for microparticle-labeled immunoassays. Analyst N/A:N/A (2018). PubMed: 29878004
  • Foo KS  et al. Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction. Mol Ther 26:1644-1659 (2018). PubMed: 29606507
  • Lv Y  et al. TGF-ß1 combined with Sal-B promotes cardiomyocyte differentiation of rat mesenchymal stem cells. Exp Ther Med 15:5359-5364 (2018). PubMed: 29904415
  • Shu C  et al. Pressure Overload in Mice With Haploinsufficiency of Striated Preferentially Expressed Gene Leads to Decompensated Heart Failure. Front Physiol 9:863 (2018). PubMed: 30042693
  • Hao W  et al. Aspirin inhibits growth and enhances cardiomyocyte differentiation of bone marrow mesenchymal stem cells. Eur J Pharmacol 827:198-207 (2018). ICC/IF . PubMed: 29551657
  • Pan B  et al. Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification. J Cell Mol Med 21:2481-2490 (2017). WB . PubMed: 28382690
  • Pozsgai ER  et al. Systemic AAV-Mediated ß-Sarcoglycan Delivery Targeting Cardiac and Skeletal Muscle Ameliorates Histological and Functional Deficits in LGMD2E Mice. Mol Ther 25:855-869 (2017). PubMed: 28284983
  • Cen M  et al. TIEG1 deficiency confers enhanced myocardial protection in the infarcted heart by mediating the Pten/Akt signalling pathway. Int J Mol Med 39:569-578 (2017). PubMed: 28204828
  • Czarna A  et al. Single-cell analysis of the fate of c-kit-positive bone marrow cells. NPJ Regen Med 2:27 (2017). PubMed: 29302361
  • Nothjunge S  et al. DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes. Nat Commun 8:1667 (2017). PubMed: 29162810
  • Lin B  et al. Culture in Glucose-Depleted Medium Supplemented with Fatty Acid and 3,3',5-Triiodo-l-Thyronine Facilitates Purification and Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Front Endocrinol (Lausanne) 8:253 (2017). PubMed: 29067001
  • Asai R  et al. Amniogenic somatopleure: a novel origin of multiple cell lineages contributing to the cardiovascular system. Sci Rep 7:8955 (2017). PubMed: 28827655
  • Didié M  et al. Immunological Properties of Murine Parthenogenetic Stem Cell-Derived Cardiomyocytes and Engineered Heart Muscle. Front Immunol 8:955 (2017). PubMed: 28855904
  • Gong H  et al. Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1. Mol Med Rep 16:787-793 (2017). ICC . PubMed: 28560388
  • Jeziorowska D  et al. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols. Int J Mol Sci 18:N/A (2017). WB ; Human . PubMed: 28587156
  • Cohen JE  et al. An innovative biologic system for photon-powered myocardium in the ischemic heart. Sci Adv 3:e1603078 (2017). IHC ; Rat . PubMed: 28630913
  • Deng S  et al. Neonatal Heart-Enriched miR-708 Promotes Proliferation and Stress Resistance of Cardiomyocytes in Rodents. Theranostics 7:1953-1965 (2017). IF ; Mouse, Rat . PubMed: 28638481
  • Wang T  et al. GDF15 is a heart-derived hormone that regulates body growth. EMBO Mol Med 9:1150-1164 (2017). IHC ; Mouse . PubMed: 28572090
  • Nishiga M  et al. MicroRNA-33 Controls Adaptive Fibrotic Response in the Remodeling Heart by Preserving Lipid Raft Cholesterol. Circ Res 120:835-847 (2017). PubMed: 27920122
  • Dal-Pra S  et al. Demethylation of H3K27 Is Essential for the Induction of Direct Cardiac Reprogramming by miR Combo. Circ Res 120:1403-1413 (2017). PubMed: 28209718
  • Sun Y  et al. Cadaveric cardiosphere-derived cells can maintain regenerative capacity and improve the heart function of cardiomyopathy. Cell Cycle 15:1248-56 (2016). PubMed: 27058215
  • Shi H  et al. Hiding inside? Intracellular expression of non-glycosylated c-kit protein in cardiac progenitor cells. Stem Cell Res 16:795-806 (2016). PubMed: 27161312
  • Zhao S  et al. Bioengineering of injectable encapsulated aggregates of pluripotent stem cells for therapy of myocardial infarction. Nat Commun 7:13306 (2016). PubMed: 27786170
  • Lundqvist A  et al. The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation. PLoS One 11:e0161629 (2016). PubMed: 27552229
  • Chiang MY  et al. Constructing 3D heterogeneous hydrogels from electrically manipulated prepolymer droplets and crosslinked microgels. Sci Adv 2:e1600964 (2016). IHC (PFA fixed) ; Mouse . PubMed: 27819046
  • Guo Y  et al. S100A1 transgenic treatment of acute heart failure causes proteomic changes in rats. Mol Med Rep 14:1538-52 (2016). WB . PubMed: 27357314
  • Liu L  et al. Enhancement of Anti-Hypoxic Activity and Differentiation of Cardiac Stem Cells by Supernatant Fluids from Cultured Macrophages that Phagocytized Dead Mesenchymal Stem Cells. Int J Mol Sci 17:N/A (2016). Flow Cyt ; Mouse . PubMed: 27447628
  • Deng S  et al. Neonatal Heart-Enriched miR-708 Promotes Differentiation of Cardiac Progenitor Cells in Rats. Int J Mol Sci 17:N/A (2016). IF . PubMed: 27338347
  • Yamakawa H  et al. Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions. Stem Cell Reports 5:1128-1142 (2015). PubMed: 26626177
  • Fu Y  et al. Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails. Cell Res 25:1013-24 (2015). IF . PubMed: 26292833
  • Avlas O  et al. TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery. PLoS One 10:e0120175 (2015). IF ; Human . PubMed: 26030867
  • Stoppel WL  et al. Anisotropic silk biomaterials containing cardiac extracellular matrix for cardiac tissue engineering. Biomed Mater 10:034105 (2015). PubMed: 25826196
  • Magli A  et al. Pax3 and Tbx5 specify whether PDGFRa+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells. Stem Cells 32:2072-83 (2014). PubMed: 24677751
  • Drummond CA  et al. Reduction of Na/K-ATPase affects cardiac remodeling and increases c-kit cell abundance in partial nephrectomized mice. Am J Physiol Heart Circ Physiol 306:H1631-43 (2014). PubMed: 24748592
  • Pinney JR  et al. Discrete microstructural cues for the attenuation of fibrosis following myocardial infarction. Biomaterials 35:8820-8 (2014). PubMed: 25047625
  • Torrado M  et al. Pitx2c is reactivated in the failing myocardium and stimulates myf5 expression in cultured cardiomyocytes. PLoS One 9:e90561 (2014). PubMed: 24595098
  • Gilsbach R  et al. Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease. Nat Commun 5:5288 (2014). PubMed: 25335909
  • Zafiriou MP  et al. Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction. Stem Cells 32:2480-91 (2014). IHC-P, Flow Cyt, ICC/IF . PubMed: 24806289
  • Weyers JJ  et al. Effects of cell grafting on coronary remodeling after myocardial infarction. J Am Heart Assoc 2:e000202 (2013). IHC-P ; Mouse . PubMed: 23723253
  • Behrens AN  et al. Nkx2-5 mediates differential cardiac differentiation through interaction with hoxa10. Stem Cells Dev 22:2211-20 (2013). PubMed: 23477547
  • Ye L  et al. Thymosin ß4 increases the potency of transplanted mesenchymal stem cells for myocardial repair. Circulation 128:S32-41 (2013). PubMed: 24030419
  • Danielson LS  et al. Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J 27:1460-7 (2013). PubMed: 23271053
  • Magli A  et al. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells 31:59-70 (2013). PubMed: 23081715
  • Noort WA  et al. Human versus porcine mesenchymal stromal cells: phenotype, differentiation potential, immunomodulation and cardiac improvement after transplantation. J Cell Mol Med 16:1827-39 (2012). PubMed: 21973026
  • Lescroart F  et al. Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing. Circ Res 111:1313-22 (2012). PubMed: 22855565
  • Fogle RL  et al. Functional proteomic analysis reveals sex-dependent differences in structural and energy-producing myocardial proteins in rat model of alcoholic cardiomyopathy. Physiol Genomics 43:346-56 (2011). WB ; Rat . PubMed: 21245415
  • Opitz E  et al. Impairment of Immunoproteasome Function by ß5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis. PLoS Pathog 7:e1002233 (2011). Flow Cyt ; Mouse . PubMed: 21909276
  • Schneider M  et al. Cell-specific detection of microRNA expression during cardiomyogenesis by combined in situ hybridization and immunohistochemistry. J Mol Histol 42:289-99 (2011). WB ; Mouse . PubMed: 21643937
  • Torrado M  et al. Targeted gene-silencing reveals the functional significance of myocardin signaling in the failing heart. PLoS One 6:e26392 (2011). PubMed: 22028870
  • Martinez-Fernandez A  et al. iPS programmed without c-MYC yield proficient cardiogenesis for functional heart chimerism. Circ Res 105:648-56 (2009). PubMed: 19696409

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