Anti-Cardiac Troponin T antibody [1C11] (ab8295)

Mouse monoclonal Cardiac Troponin T antibody [1C11]. Validated in WB, IP, ELISA, IHC, Flow Cyt, ICC/IF, sELISA and tested in Mouse, Rat, Dog, Human. Cited in 79 publication(s).

Publishing research using ab8295? Please let us know so that we can cite the reference in this datasheet.

ab8295 has been referenced in 84 publications.

  • Zhang J  et al. Insulin gene enhancer binding protein 1 induces adipose tissue-derived stem cells to differentiate into pacemaker-like cells. Int J Mol Med 43:879-889 (2019). PubMed: 30483766
  • Li S  et al. Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1. Biochim Biophys Acta Mol Basis Dis N/A:N/A (2019). PubMed: 30677512
  • Waas M  et al. Are These Cardiomyocytes? Protocol Development Reveals Impact of Sample Preparation on the Accuracy of Identifying Cardiomyocytes by Flow Cytometry. Stem Cell Reports 12:395-410 (2019). PubMed: 30686762
  • Slotvitsky M  et al. Arrhythmogenicity Test Based on a Human-Induced Pluripotent Stem Cell (iPSC)-Derived Cardiomyocyte Layer. Toxicol Sci 168:70-77 (2019). PubMed: 30388253
  • Liu R  et al. Tead1 is required for perinatal cardiomyocyte proliferation. PLoS One 14:e0212017 (2019). PubMed: 30811446
  • Ren L  et al. A Disintegrin and Metalloprotease-22 Attenuates Hypertrophic Remodeling in Mice Through Inhibition of the Protein Kinase B Signaling Pathway. J Am Heart Assoc 7:N/A (2018). PubMed: 29358191
  • Shafa M  et al. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne) 5:69 (2018). PubMed: 29600249
  • Vujic A  et al. Exercise induces new cardiomyocyte generation in the adult mammalian heart. Nat Commun 9:1659 (2018). PubMed: 29695718
  • Cui C  et al. Atrial remodeling and metabolic dysfunction in idiopathic isolated fibrotic atrial cardiomyopathy. Int J Cardiol 265:155-161 (2018). ICC/IF . PubMed: 29706431
  • Zhang J  et al. Pericardial application as a new route for implanting stem-cell cardiospheres to treat myocardial infarction. J Physiol 596:2037-2054 (2018). PubMed: 29736937
  • Wang X & Song Q Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway. Cell Mol Biol Lett 23:21 (2018). PubMed: 29760744
  • Geng L  et al. Probing flecainide block of INa using human pluripotent stem cell-derived ventricular cardiomyocytes adapted to automated patch-clamping and 2D monolayers. Toxicol Lett 294:61-72 (2018). Flow Cyt . PubMed: 29758359
  • Zhou H  et al. Melatonin therapy for diabetic cardiomyopathy: A mechanism involving Syk-mitochondrial complex I-SERCA pathway. Cell Signal 47:88-100 (2018). ICC/IF . PubMed: 29601906
  • Selga E  et al. Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient. J Mol Cell Cardiol 114:10-19 (2018). ICC/IF . PubMed: 29024690
  • Zhou H  et al. Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury. J Pineal Res N/A:e12503 (2018). PubMed: 29770487
  • Eley L  et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. Elife 7:N/A (2018). PubMed: 29956664
  • Ferrer CM  et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev 32:373-388 (2018). PubMed: 29555651
  • Fan X  et al. Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis. Cell Res 28:730-745 (2018). PubMed: 29867213
  • Hao W  et al. Aspirin inhibits growth and enhances cardiomyocyte differentiation of bone marrow mesenchymal stem cells. Eur J Pharmacol 827:198-207 (2018). Flow Cyt . PubMed: 29551657
  • Yu W  et al. Mst1 promotes cardiac ischemia-reperfusion injury by inhibiting the ERK-CREB pathway and repressing FUNDC1-mediated mitophagy. J Physiol Sci N/A:N/A (2018). PubMed: 29961191
  • Ma ZG  et al. Long title: C1q-tumor necrosis factor-related protein-3 exacerbates cardiac hypertrophy in mice. Cardiovasc Res N/A:N/A (2018). PubMed: 30407523
  • Gartz M  et al. Exosomes exert cardioprotection in dystrophin-deficient cardiomyocytes via ERK1/2-p38/MAPK signaling. Sci Rep 8:16519 (2018). PubMed: 30410044
  • Fan Y  et al. Wnt/ß-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes. Stem Cell Res Ther 9:338 (2018). PubMed: 30526659
  • Asp M  et al. Spatial detection of fetal marker genes expressed at low level in adult human heart tissue. Sci Rep 7:12941 (2017). IHC ; Human . PubMed: 29021611
  • Malek Mohammadi M  et al. The transcription factor GATA4 promotes myocardial regeneration in neonatal mice. EMBO Mol Med 9:265-279 (2017). PubMed: 28053183
  • Huang Y  et al. Age-Dependent Oxidative DNA Damage Does Not Correlate with Reduced Proliferation of Cardiomyocytes in Humans. PLoS One 12:e0170351 (2017). PubMed: 28099512
  • Hu Y  et al. Identification of cardiac hemo-vascular precursors and their requirement of sphingosine-1-phosphate receptor 1 for heart development. Sci Rep 7:45205 (2017). PubMed: 28338096
  • Liu B  et al. Cardiac resident macrophages are involved in hypoxia-induced postnatal cardiomyocyte proliferation. Mol Med Rep 15:3541-3548 (2017). PubMed: 28393210
  • See K  et al. Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo. Nat Commun 8:225 (2017). PubMed: 28790305
  • Liao HH  et al. Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting I?Ba/NF?B and Enhancing Nrf2/HO-1. Oxid Med Cell Longev 2017:8370593 (2017). PubMed: 29147465
  • Gu Q  et al. Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations. Stem Cell Reports 9:366-380 (2017). PubMed: 28506532
  • He ZQ  et al. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening. Cell Rep 20:2227-2237 (2017). PubMed: 28854370
  • Zheng C  et al. Gastrodin Inhibits Store-Operated Ca(2+) Entry and Alleviates Cardiac Hypertrophy. Front Pharmacol 8:222 (2017). WB ; Mouse . PubMed: 28487655
  • Cui C  et al. Structural and electrophysiological dysfunctions due to increased endoplasmic reticulum stress in a long-term pacing model using human induced pluripotent stem cell-derived ventricular cardiomyocytes. Stem Cell Res Ther 8:109 (2017). ICC/IF ; Human . PubMed: 28490375
  • Mathison M  et al. In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration. J Thorac Cardiovasc Surg 153:329-339.e3 (2017). ICC/IF ; Rat . PubMed: 27773576
  • Pok S  et al. Full-Thickness Heart Repair with an Engineered Multilayered Myocardial Patch in Rat Model. Adv Healthc Mater 6:N/A (2017). PubMed: 28081298
  • Li T  et al. The spontaneous differentiation and chromosome loss in iPSCs of human trisomy 18 syndrome. Cell Death Dis 8:e3149 (2017). PubMed: 29072700
  • Ye L  et al. Cardiomyocytes in Young Infants With Congenital Heart Disease: a Three-Month Window of Proliferation. Sci Rep 6:23188 (2016). IF, Flow Cyt . PubMed: 26976548
  • Seo HH  et al. The role of nuclear factor of activated T cells during phorbol myristate acetate-induced cardiac differentiation of mesenchymal stem cells. Stem Cell Res Ther 7:90 (2016). ICC/IF ; Human . PubMed: 27405982
  • KalantarMotamedi Y  et al. Systematic selection of small molecules to promote differentiation of embryonic stem cells and experimental validation for generating cardiomyocytes. Cell Death Discov 2:16007 (2016). WB . PubMed: 27551501
  • Ikeda Y  et al. A novel intranuclear RNA vector system for long-term stem cell modification. Gene Ther 23:256-62 (2016). PubMed: 26632671
  • Liu H  et al. Resveratrol Enhances Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells through Inhibiting Canonical WNT Signal Pathway and Enhancing Serum Response Factor-miR-1 Axis. Stem Cells Int 2016:2524092 (2016). PubMed: 26798354
  • Tang Y  et al. Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1. Stem Cells 34:1527-40 (2016). PubMed: 26866517
  • Wang H  et al. Generation of electrophysiologically functional cardiomyocytes from mouse induced pluripotent stem cells. Stem Cell Res 16:522-30 (2016). PubMed: 26972055
  • Månsson-Broberg A  et al. Wnt/ß-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells. Stem Cell Reports 6:607-617 (2016). PubMed: 27052314
  • Ujhelly O  et al. Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation. Stem Cells Dev 24:2193-205 (2015). PubMed: 26110923
  • Wang Y  et al. Nitric Oxide-cGMP-PKG Pathway Acts on Orai1 to Inhibit the Hypertrophy of Human Embryonic Stem Cell-Derived Cardiomyocytes. Stem Cells 33:2973-84 (2015). PubMed: 26269433
  • Ye L  et al. Decreased Yes-Associated Protein-1 (YAP1) Expression in Pediatric Hearts with Ventricular Septal Defects. PLoS One 10:e0139712 (2015). IF, Flow Cyt . PubMed: 26426694
  • Driscoll CB  et al. Nuclear reprogramming with a non-integrating human RNA virus. Stem Cell Res Ther 6:48 (2015). PubMed: 25889591
  • Suhaeri M  et al. Cardiomyoblast (h9c2) differentiation on tunable extracellular matrix microenvironment. Tissue Eng Part A 21:1940-51 (2015). PubMed: 25836924
  • Kropp EM  et al. Inhibition of an NAD? salvage pathway provides efficient and selective toxicity to human pluripotent stem cells. Stem Cells Transl Med 4:483-93 (2015). PubMed: 25834119
  • Davy PM  et al. Human adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction. Stem Cells Cloning 8:135-48 (2015). ICC . PubMed: 26604802
  • Bagno LL  et al. Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy. J Am Heart Assoc 4: (2015). IHC ; Pig . PubMed: 25827134
  • Poggioli T  et al. Circulating Growth Differentiation Factor 11/8 Levels Decline with Age. Circ Res N/A:N/A (2015). MS ; Mouse . PubMed: 26489925
  • Szebényi K  et al. Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling. Sci Rep 5:12645 (2015). IHC ; Rat . PubMed: 26234466
  • Malik A  et al. Exogenous SDF-1a Protects Human Myocardium from Hypoxia-Reoxygenation Injury via CXCR4. Cardiovasc Drugs Ther N/A:N/A (2015). IHC-Fr, IF ; Human . PubMed: 26482377
  • Jiang J  et al. Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. Proc Natl Acad Sci U S A 112:9046-51 (2015). IHC-P ; Mouse . PubMed: 26153423
  • Singh AP & Archer TK Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. Nucleic Acids Res 42:2958-75 (2014). IHC-P ; Mouse . PubMed: 24335282
  • Yu ZY  et al. RhoA/ROCK Signaling and Pleiotropic a1A-Adrenergic Receptor Regulation of Cardiac Contractility. PLoS One 9:e99024 (2014). WB ; Mouse . PubMed: 24919197
  • Feng Z  et al. Expression of microRNA-1, microRNA-133a and Hand2 protein in cultured embryonic rat cardiomyocytes. In Vitro Cell Dev Biol Anim 50:700-6 (2014). Rat . PubMed: 24789724
  • Pacak CA  et al. Superparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells. PLoS One 9:e108695 (2014). IHC-P ; Rat . PubMed: 25250622
  • Hua K  et al. Cardiomyocyte cytokinesis score: a potential method for cardiomyocyte proliferation. Cell Biol Int 38:1032-40 (2014). PubMed: 24800698
  • Soh BS  et al. N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment. Cell Res 24:1420-32 (2014). IHC-Fr ; Mouse . PubMed: 25367124
  • Burridge PW  et al. Chemically defined generation of human cardiomyocytes. Nat Methods 11:855-60 (2014). Flow Cyt . PubMed: 24930130
  • Behrens AN  et al. Nkx2-5 mediates differential cardiac differentiation through interaction with hoxa10. Stem Cells Dev 22:2211-20 (2013). PubMed: 23477547
  • Chetty S  et al. A simple tool to improve pluripotent stem cell differentiation. Nat Methods 10:553-6 (2013). Human . PubMed: 23584186
  • Gaber N  et al. Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation. Am J Pathol 183:720-34 (2013). IHC, Flow Cyt . PubMed: 23871585
  • Raynaud CM  et al. Human embryonic stem cell derived mesenchymal progenitors express cardiac markers but do not form contractile cardiomyocytes. PLoS One 8:e54524 (2013). Flow Cyt . PubMed: 23342164
  • Ivashchenko CY  et al. Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype. Am J Physiol Heart Circ Physiol 305:H913-22 (2013). PubMed: 23832699
  • Lim SY  et al. Ischemic preconditioning promotes intrinsic vascularization and enhances survival of implanted cells in an in vivo tissue engineering model. Tissue Eng Part A 18:2210-9 (2012). PubMed: 22651554
  • Islas JF  et al. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A 109:13016-21 (2012). PubMed: 22826236
  • Liu F  et al. ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling. Blood 119:3295-305 (2012). Flow Cyt ; Mouse . PubMed: 22343916
  • Ye S  et al. Pleiotropy of Glycogen Synthase Kinase-3 Inhibition by CHIR99021 Promotes Self-Renewal of Embryonic Stem Cells from Refractory Mouse Strains. PLoS One 7:e35892 (2012). ICC/IF . PubMed: 22540008
  • Abdul-Ghani M  et al. Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals. Mol Cell Biol 31:163-78 (2011). WB ; Mouse . PubMed: 21041481
  • Smart N  et al. De novo cardiomyocytes from within the activated adult heart after injury. Nature 474:640-4 (2011). IHC-Fr ; Mouse . PubMed: 21654746
  • Ma J  et al. High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am J Physiol Heart Circ Physiol 301:H2006-17 (2011). PubMed: 21890694
  • Wang Y  et al. Dioxin exposure disrupts the differentiation of mouse embryonic stem cells into cardiomyocytes. Toxicol Sci 115:225-37 (2010). Flow Cyt ; Mouse . PubMed: 20130022
  • Brown ME  et al. Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes. PLoS One 5:e11373 (2010). Flow Cyt ; Human . PubMed: 20617191
  • Evseenko D  et al. Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells. Proc Natl Acad Sci U S A 107:13742-7 (2010). Flow Cyt ; Human . PubMed: 20643952
  • Torres R & Ramirez JC A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart. PLoS One 4:e7570 (2009). IHC-FoFr ; Mouse . PubMed: 19859557
  • Takehara T  et al. Potential existence of stem cells with multiple differentiation abilities to three different germ lineages in mouse neurospheres. Stem Cells Dev 18:1433-40 (2009). WB, ICC/IF ; Mouse . PubMed: 19601713
  • Deb A  et al. SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. Stem Cells 26:35-44 (2008). WB, IHC (PFA fixed) ; Mouse . PubMed: 17916803
  • Palmer BM  et al. Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex. Am J Physiol Heart Circ Physiol 294:H1939-47 (2008). PubMed: 18281382
  • Lindsley RC  et al. Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell 3:55-68 (2008). ICC/IF, Flow Cyt . PubMed: 18593559

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
For licensing inquiries, please contact partnerships@abcam.com

Sign up