Overview

  • Product name

  • Description

    Rabbit polyclonal to Carma 3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment within Human Carma 3 aa 341-630 (internal sequence). The exact sequence is proprietary.
    Database link: Q9BWT7

  • Positive control

    • 293T, H1299, MOLT4 and Raji whole cell lysates.
  • General notes

    Protein previously labeled as CARD10.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab137383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 116 kDa.

Target

  • Function

    Activates NF-kappa-B via BCL10 and IKK.
  • Tissue specificity

    Detected in adult heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney.
  • Sequence similarities

    Contains 1 CARD domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Bcl10 binding protein and activator of NFKB antibody
    • BIMP1 antibody
    • CAR10_HUMAN antibody
    • CARD 10 antibody
    • CARD containing MAGUK 3 protein antibody
    • CARD-containing MAGUK 3 antibody
    • CARD-containing MAGUK protein 3 antibody
    • CARD10 antibody
    • Carma 3 antibody
    • CARMA3 antibody
    • Caspase Recruitment Domain family member 10 antibody
    • Caspase recruitment domain-containing protein 10 antibody
    see all

Images

  • Anti-Carma 3 antibody (ab137383) at 1/1000 dilution + 293T cell lysate at 30 µg

    Predicted band size: 116 kDa



    7.5% SDS PAGE

References

This product has been referenced in:

  • Lin J  et al. MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10. FASEB J 30:3216-26 (2016). Read more (PubMed: 27297585) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab137383.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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