Key features and details
- Potent acid ceramidase inhibitor. Antimetabolite agent.
- CAS Number: 61422-45-5
- Purity: > 97%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameCarmofur, Antimetabolite agent
DescriptionPotent acid ceramidase inhibitor. Antimetabolite agent.
Biological descriptionPotent acid ceramidase inhibitor (IC50 = 29 nM). Antimetabolite agent. cytostatic pyrimidine analogue derivative of fluorouracil (Asc 2387) . Shows antitumor effects in vivo. Orally active.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142653 has not yet been referenced specifically in any publications.