• Product name
    Anti-Casein Kinase 1 delta / CSNK1D antibody
    See all Casein Kinase 1 delta / CSNK1D primary antibodies
  • Description
    Goat polyclonal to Casein Kinase 1 delta / CSNK1D
  • Host species
  • Specificity
    ab10877 is specific for human Casein Kinase 1 delta / CSNK1D.
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human Casein Kinase 1 delta/ CSNK1D aa 310-327 (C terminal).

  • General notes

    Previously labelled as Casein Kinase 1 delta. 



Our Abpromise guarantee covers the use of ab10877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
IHC-P 1/200. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Function
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm.
  • Tissue specificity
    Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes.
  • Involvement in disease
    Defects in CSNK1D are a cause of familial advanced sleep-phase syndrome (FASPS) [MIM:604348]. FASPS is characterized by very early sleep onset and offset. Individuals are 'morning larks' with a 4 hours advance of the sleep, temperature and melatonin rhythms.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    Autophosphorylated on serine and threonine residues.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Casein Kinase 1 delta antibody
    • Casein kinase I delta isoform antibody
    • Casein kinase I isoform delta antibody
    • CKI delta antibody
    • CKI-delta antibody
    • CKId antibody
    • CKIdelta antibody
    • CSNK 1D antibody
    • CSNK1D antibody
    • HCKID antibody
    • KC1D_HUMAN antibody
    • Protein kinase CK1 delta antibody
    see all


  • ab10877 at 1/200 dilution staining Casein Kinase 1 delta / CSNK1D in mouse skeletal muscle tissue section by Immunohistochemistry. Tissue samples from 4 to 6 week old BALB/c mice were immediately removed after killing and immersion fixed in Bouin's solution. Primary antibody was used for 40 minutes at RT. Specific antibody binding was visualised by the peroxidase reaction using DAB as substrate-chromogen.


This product has been referenced in:
  • Lin SH  et al. Casein kinase 1 epsilon expression predicts poorer prognosis in low T-stage oral cancer patients. Int J Mol Sci 15:2876-91 (2014). IHC-P ; Human . Read more (PubMed: 24557581) »
  • Löhler J  et al. Immunohistochemical characterisation of cell-type specific expression of CK1delta in various tissues of young adult BALB/c mice. PLoS One 4:e4174 (2009). IHC-P ; Mouse . Read more (PubMed: 19137063) »
See all 4 Publications for this product

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