Anti-Caspase-1 antibody (ab1872)

Rabbit polyclonal Caspase-1 antibody. Validated in WB, IHC, ICC/IF and tested in Mouse, Rat, Human. Cited in 29 publication(s). Independently reviewed in 6 review(s).

Publishing research using ab1872? Please let us know so that we can cite the reference in this datasheet.

ab1872 has been referenced in 32 publications.

  • Nakamura H  et al. Altered expression of inflammasomes in Hirschsprung's disease. Pediatr Surg Int 35:15-20 (2019). PubMed: 30386901
  • Soliman NA  et al. The possible ameliorative effect of simvastatin versus sulfasalazine on acetic acid induced ulcerative colitis in adult rats. Chem Biol Interact 298:57-65 (2019). PubMed: 30408459
  • Banerjee S  et al. Sulphur dioxide ameliorates colitis related pathophysiology and inflammation. Toxicology 412:63-78 (2019). PubMed: 30503585
  • Mai CT  et al. Palmatine attenuated dextran sulfate sodium (DSS)-induced colitis via promoting mitophagy-mediated NLRP3 inflammasome inactivation. Mol Immunol 105:76-85 (2019). PubMed: 30496979
  • Xu TZ  et al. Ginsenoside Rg1 protects against H2O2-induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro. Int J Mol Med 43:717-726 (2019). PubMed: 30535505
  • Xu T  et al. NADPH oxidase 2-mediated NLRP1 inflammasome activation involves in neuronal senescence in hippocampal neurons in vitro. Int Immunopharmacol 69:60-70 (2019). PubMed: 30677569
  • Ding HG  et al. Hypercapnia induces IL-1ß overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats. J Neuroinflammation 15:4 (2018). PubMed: 29304864
  • Feng J  et al. Unconjugated bilirubin induces pyroptosis in cultured rat cortical astrocytes. J Neuroinflammation 15:23 (2018). PubMed: 29357878
  • Pan Z  et al. miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis. J Neuroinflammation 15:29 (2018). PubMed: 29386025
  • Han Y  et al. Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis. Redox Biol 16:32-46 (2018). PubMed: 29475133
  • Song HM  et al. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS. Int J Mol Med 42:193-207 (2018). PubMed: 29620148
  • Thankam FG  et al. Association of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon. Sci Rep 8:8918 (2018). IHC-P ; Rat . PubMed: 29891998
  • Lee J  et al. Physical activity protects NLRP3 inflammasome-associated coronary vascular dysfunction in obese mice. Physiol Rep 6:e13738 (2018). PubMed: 29932503
  • Kang R  et al. Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis. Cell Host Microbe 24:97-108.e4 (2018). PubMed: 29937272
  • Turtle JD  et al. Pain Input After Spinal Cord Injury (SCI) Undermines Long-Term Recovery and Engages Signal Pathways That Promote Cell Death. Front Syst Neurosci 12:27 (2018). PubMed: 29977195
  • Tang Y  et al. Cathepsin B inhibition ameliorates the non-alcoholic steatohepatitis through suppressing caspase-1 activation. J Physiol Biochem N/A:N/A (2018). PubMed: 30019185
  • Gao H  et al. Anti-depressant-like effect of atractylenolide I in a mouse model of depression induced by chronic unpredictable mild stress. Exp Ther Med 15:1574-1579 (2018). PubMed: 29434743
  • Wan L  et al. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Exp Ther Med 15:2429-2435 (2018). PubMed: 29467847
  • Yang X  et al. Pretreatment with low-dose fimasartan ameliorates NLRP3 inflammasome-mediated neuroinflammation and brain injury after intracerebral hemorrhage. Exp Neurol 310:22-32 (2018). PubMed: 30171865
  • Xiao N  et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol 8:43 (2017). PubMed: 28261091
  • Cao S  et al. Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation. Sci Rep 7:2417 (2017). WB . PubMed: 28546552
  • Shi X  et al. NLRP3-inflammasomes are triggered by age-related hearing loss in the inner ear of mice. Am J Transl Res 9:5611-5618 (2017). PubMed: 29312513
  • Jiang P  et al. Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome. J Neuroinflammation 14:239 (2017). WB ; Rat . PubMed: 29212498
  • Luo X  et al. Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice. Sci Rep 7:16374 (2017). PubMed: 29180692
  • Li Y  et al. Succinate/NLRP3 Inflammasome Induces Synovial Fibroblast Activation: Therapeutical Effects of Clematichinenoside AR on Arthritis. Front Immunol 7:532 (2016). WB ; Rat . PubMed: 28003810
  • Puyang Z  et al. Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice. Sci Rep 6:20998 (2016). Mouse . PubMed: 26893104
  • Bakele M  et al. Localization and functionality of the inflammasome in neutrophils. J Biol Chem 289:5320-9 (2014). WB ; Human . PubMed: 24398679
  • Luo B  et al. NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model. PLoS One 9:e104771 (2014). WB, IHC ; Rat . PubMed: 25136835
  • Aries A  et al. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis 5:e1566 (2014). ICC/IF ; Rat . PubMed: 25501827
  • Gu H  et al. Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis. Cell Death Dis 4:e816 (2013). Rat . PubMed: 24091659
  • Ozkan G  et al. How does colistin-induced nephropathy develop and can it be treated? Antimicrob Agents Chemother 57:3463-9 (2013). PubMed: 23629704
  • Harris J  et al. Autophagy controls IL-1{beta} secretion by targeting pro-IL-1{beta} for degradation. J Biol Chem : (2011). WB ; Mouse . PubMed: 21228274

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
For licensing inquiries, please contact partnerships@abcam.com

Sign up