Product nameAnti-Caspase-2 antibody
DescriptionRabbit polyclonal to Caspase-2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment corresponding to Human Caspase-2 aa 1-201. BC002427
MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQ LLLSELLEHL LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQA FDAFCEALRETKQGHLEDMLLT TLSGLQHVLPPLSCDYDLSLPFPVCE SCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT PEFYQTHFQLAYRL QSRPRGL
Database link: P42575
- Human fetal kidney and lung tissue lysate; Human urinary bladder tissue
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab182657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/300.|
|WB||1/1000 - 1/2000. Predicted molecular weight: 51 kDa.|
FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Tissue specificityExpressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Sequence similaritiesBelongs to the peptidase C14A family.
Contains 1 CARD domain.
modificationsThe mature protease can process its own propeptide, but not that of other caspases.
- Information by UniProt
- Casp 2L Pro antibody
- CASP-2 antibody
- Casp2 antibody
Immunohistochemical analysis of paraffin-embedded Human urinary bladder tissue labeling active Caspase 2 using ab182657 at 1/100 dilution. The right panel is treated with the fusion protein.
All lanes : Anti-Caspase-2 antibody (ab182657) at 1/950 dilution
Lane 1 : Human fetal kidney lysate
Lane 2 : Human fetal lung lysate
Lysates/proteins at 30 µg per lane.
All lanes : Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution
Predicted band size: 51 kDa
Exposure time: 2 minutes
10% SDS PAGE
ab182657 has not yet been referenced specifically in any publications.