Anti-Caspase-3 antibody (ab44976)

Rabbit polyclonal Caspase-3 antibody. Validated in WB, IP, IHC, ICC/IF and tested in Mouse, Rat, Rabbit, Human, Monkey. Cited in 57 publication(s). Independently reviewed in 3 review(s).

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ab44976 has been referenced in 60 publications.

  • Liu L  et al. PTEN inhibits non-small cell lung cancer cell growth by promoting G0/G1 arrest and cell apoptosis. Oncol Lett 17:1333-1340 (2019). PubMed: 30655903
  • Tang YJ  et al. Bisperoxovanadium protects against spinal cord injury by regulating autophagy via activation of ERK1/2 signaling. Drug Des Devel Ther 13:513-521 (2019). PubMed: 30774313
  • Jin X  et al. MicroRNA-105 promotes epithelial-mesenchymal transition of nonsmall lung cancer cells through upregulating Mcl-1. J Cell Biochem 120:5880-5888 (2019). PubMed: 30317672
  • Tang YH  et al. ß-Ecdysterone promotes autophagy and inhibits apoptosis in osteoporotic rats. Mol Med Rep 17:1591-1598 (2018). PubMed: 29138818
  • da Silva VK  et al. Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload. Transl Psychiatry 8:176 (2018). PubMed: 30177808
  • Xie X  et al. Homeobox C10 knockdown suppresses cell proliferation and promotes cell apoptosis in osteosarcoma cells through regulating caspase 3. Onco Targets Ther 11:473-482 (2018). PubMed: 29403292
  • Liu JJ  et al. MicroRNA-138 promotes proliferation and suppresses mitochondrial depolarization in human pulmonary artery smooth muscle cells through targeting TASK-1. Mol Med Rep 17:3021-3027 (2018). PubMed: 29257242
  • Yu X  et al. Regulatory effects of four ginsenoside monomers in humoral immunity of systemic lupus erythematosus. Exp Ther Med 15:2097-2103 (2018). PubMed: 29434811
  • Murai K  et al. Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations. Cell Stem Cell 23:687-699.e8 (2018). PubMed: 30269904
  • Liu Y  et al. Protective Effect of Hydrogen on Sodium Iodate-Induced Age-Related Macular Degeneration in Mice. Front Aging Neurosci 10:389 (2018). PubMed: 30564112
  • Zhuang X & Lu M The potential functions of FAM46C in oral squamous cell carcinoma. Onco Targets Ther 11:8915-8923 (2018). PubMed: 30573978
  • Zhao Q  et al. Rhein protects against cerebral ischemic-/reperfusion-induced oxidative stress and apoptosis in rats. Int J Mol Med 41:2802-2812 (2018). PubMed: 29436613
  • Wang J  et al. Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway. Exp Ther Med 15:3650-3658 (2018). PubMed: 29545895
  • Lee YL  et al. Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways. Sci Rep 8:5358 (2018). PubMed: 29599473
  • Tang C  et al. Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma. Oncol Lett 15:7060-7068 (2018). PubMed: 29731872
  • Du J  et al. Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression. Braz J Med Biol Res 51:e7061 (2018). PubMed: 29694508
  • Nassief Beshay EV  et al. Toxoplasma gondii as a possible causative pathogen of type-1 diabetes mellitus: Evidence from case-control and experimental studies. Exp Parasitol 188:93-101 (2018). IHC-P . PubMed: 29627328
  • Qin T  et al. Effect of Period 2 on the proliferation, apoptosis and migration of osteosarcoma cells, and the corresponding mechanisms. Oncol Lett 16:2668-2674 (2018). PubMed: 30013663
  • Yu W  et al. Astragaloside IV reduces the hypoxia-induced injury in PC-12 cells by inhibiting expression of miR-124. Biomed Pharmacother 106:419-425 (2018). PubMed: 29990829
  • Guo Z  et al. Beta-elemene increases chemosensitivity to 5-fluorouracil through down-regulating microRNA-191 expression in colorectal carcinoma cells. J Cell Biochem 119:7032-7039 (2018). PubMed: 29737579
  • Zheng Y  et al. Pinocembrin induces ER stress mediated apoptosis and suppresses autophagy in melanoma cells. Cancer Lett 431:31-42 (2018). PubMed: 29807112
  • Liu G & Zhang W Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes. Braz J Med Biol Res 51:e6896 (2018). PubMed: 29898032
  • Sun KX & Xia HW Pachymic acid inhibits growth and induces cell cycle arrest and apoptosis in gastric cancer SGC-7901 cells. Oncol Lett 16:2517-2524 (2018). PubMed: 30013646
  • Hu X  et al. Long non-coding RNA GAS5 aggravates hypoxia injury in PC-12 cells via down-regulating miR-124. J Cell Biochem 119:6765-6774 (2018). PubMed: 29737538
  • Wang L  et al. The apoptotic effect of Zoledronic acid on the nasopharyngeal carcinoma cells via ROS mediated chloride channel activation. Clin Exp Pharmacol Physiol 45:1019-1027 (2018). PubMed: 29884989
  • Jiang N  et al. TUG1 alleviates hypoxia injury by targeting miR-124 in H9c2 cells. Biomed Pharmacother 103:1669-1677 (2018). WB . PubMed: 29864957
  • Wang J  et al. TRIM65 is a potential oncogenic protein via ERK1/2 on Jurkat and Raji cells: A therapeutic target in human lymphoma malignancies. Cell Biol Int N/A:N/A (2018). WB ; Human . PubMed: 30039885
  • Zhang J  et al. Downregulation of tyrosine threonine kinase inhibits tumor growth via G2/M arrest in human endometrioid endometrial adenocarcinoma. Tumour Biol 39:1010428317712444 (2017). PubMed: 28718377
  • Zhang R  et al. Mir-30d suppresses cell proliferation of colon cancer cells by inhibiting cell autophagy and promoting cell apoptosis. Tumour Biol 39:1010428317703984 (2017). PubMed: 28651493
  • Singh A  et al. Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen. Front Immunol 8:183 (2017). PubMed: 28289414
  • Ren T  et al. The Combination of Blueberry Juice and Probiotics Ameliorate Non-Alcoholic Steatohepatitis (NASH) by Affecting SREBP-1c/PNPLA-3 Pathway via PPAR-a. Nutrients 9:N/A (2017). PubMed: 28264426
  • Xie D  et al. Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury. Oncotarget 8:24154-24162 (2017). WB ; Rat . PubMed: 28445993
  • Liu X  et al. Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Int J Chron Obstruct Pulmon Dis 12:1309-1324 (2017). WB ; Rat . PubMed: 28496315
  • Lin X  et al. Antitumor effects and the underlying mechanism of licochalcone A combined with 5-fluorouracil in gastric cancer cells. Oncol Lett 13:1695-1701 (2017). WB ; Human . PubMed: 28454311
  • Stansborough RL  et al. Fractionated abdominal irradiation induces intestinal microvascular changes in an in vivo model of radiotherapy-induced gut toxicity. Support Care Cancer 25:1973-1983 (2017). PubMed: 28175996
  • Zhang Y  et al. An Extract from Shrimp Processing By-Products Protects SH-SY5Y Cells from Neurotoxicity Induced by Aß25-35. Mar Drugs 15:N/A (2017). WB ; Human . PubMed: 28327516
  • Li SD  et al. G-CSF Indirectly Induces Apoptosis of Osteoblasts During Hematopoietic Stem Cell Mobilization. Clin Transl Sci 10:287-291 (2017). IHC-P ; Mouse . PubMed: 28556597
  • Ambrosius B  et al. Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection. J Neuroinflammation 14:92 (2017). IHC-Fr ; Rat . PubMed: 28446186
  • Wang C  et al. Krüppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling. Oncotarget 8:100358-100370 (2017). PubMed: 29245984
  • de Perini A  et al. The p75NTR-mediated effect of nerve growth factor in L6C5 myogenic cells. BMC Res Notes 10:686 (2017). PubMed: 29202822
  • Samara P  et al. A fragment of the alarmin prothymosin a as a novel biomarker in murine models of bacteria-induced sepsis. Oncotarget 8:48635-48649 (2017). PubMed: 28611290
  • Yu J  et al. Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation. Int J Mol Med 40:1185-1193 (2017). PubMed: 28849106
  • Dang JH  et al. Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2. Oncol Lett 14:7557-7564 (2017). PubMed: 29344202
  • Webster MK  et al. Evidence of BrdU-positive retinal neurons after application of an Alpha7 nicotinic acetylcholine receptor agonist. Neuroscience 346:437-446 (2017). PubMed: 28147247
  • Fan G  et al. Danshensu alleviates cardiac ischaemia/reperfusion injury by inhibiting autophagy and apoptosis via activation of mTOR signalling. J Cell Mol Med 20:1908-19 (2016). Rat . PubMed: 27385290
  • Yang B  et al. Hyperoside protects human primary melanocytes against H2O2-induced oxidative damage. Mol Med Rep 13:4613-9 (2016). WB . PubMed: 27082158
  • Feng C  et al. Lycopene protects human SH-SY5Y neuroblastoma cells against hydrogen peroxide-induced death via inhibition of oxidative stress and mitochondria-associated apoptotic pathways. Mol Med Rep 13:4205-14 (2016). PubMed: 27035331
  • Cao LH  et al. Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts. Sci Rep 6:18706 (2016). WB ; Human . PubMed: 26729257
  • Xu M  et al. Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proc Natl Acad Sci U S A 112:893-8 (2015). IHC-Fr ; Mouse . PubMed: 25561540
  • Liu KM  et al. Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. Am J Physiol Renal Physiol 309:F318-31 (2015). WB ; Rat . PubMed: 26109091
  • He Y  et al. Inhibition of high glucose-induced apoptosis by uncoupling protein 2 in human umbilical vein endothelial cells. Int J Mol Med 33:1275-81 (2014). PubMed: 24584700
  • Pedroni SM  et al. Complement inhibition and statins prevent fetal brain cortical abnormalities in a mouse model of preterm birth. Biochim Biophys Acta 1842:107-15 (2014). Mouse . PubMed: 24184716
  • Onishi M  et al. Gene expression profiling of the anti-glioma effect of Cilengitide. Springerplus 2:160 (2013). WB ; Human . PubMed: 23667810
  • Wang X  et al. Microcystin (-LR) induced testicular cell apoptosis via up-regulating apoptosis-related genes in vivo. Food Chem Toxicol 60:309-17 (2013). PubMed: 23891578
  • Jonecová Z  et al. The immediate response of jejunal mucosa to small bowel heterotopic allotransplatation in rats. Tissue Cell N/A:N/A (2013). PubMed: 24079856
  • Esteves JC  et al. Dynamics of bone healing after osteotomy with piezosurgery or conventional drilling -- histomorphometrical, immunohistochemical, and molecular analysis. J Transl Med 11:221 (2013). IHC ; Rat . PubMed: 24053147
  • Zha W  et al. Roles of Mir-144-ZFX Pathway in Growth Regulation of Non-Small-Cell Lung Cancer. PLoS One 8:e74175 (2013). PubMed: 24066116
  • Taylor SM  et al. Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels. Blood : (2010). ICC/IF ; Mouse . PubMed: 20664058
  • Chen C  et al. Hydrogen-rich saline protects against spinal cord injury in rats. Neurochem Res 35:1111-8 (2010). IHC-P ; Rat . PubMed: 20354783
  • Capilla-Gonzalez V  et al. Postnatal exposure to N-ethyl-N-nitrosurea disrupts the subventricular zone in adult rodents. Eur J Neurosci 32:1789-99 (2010). IHC-FrFl ; Mouse . PubMed: 21044178

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