Overview

  • Product name

  • Description

    Rabbit polyclonal to Caspase-5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-5 (internal sequence).
    Database link: P51878

  • Positive control

    • Ramos cell lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab62401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 2 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).

Target

  • Function

    Mediator of programmed cell death (apoptosis).
  • Tissue specificity

    Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
  • Sequence similarities

    Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Post-translational
    modifications

    The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apoptosis related cysteine protease antibody
    • CASP-5 antibody
    • CASP5 antibody
    • CASP5_HUMAN antibody
    • Caspase-5 subunit p10 antibody
    • ICE(rel)-III antibody
    • ICERELIII antibody
    • ICH 3 antibody
    • ICH 3 protease antibody
    • Protease ICH-3 antibody
    • Protease TY antibody
    • TY antibody
    • TY protease antibody
    see all

Images

  • Lane 1 : Anti-Caspase-5 antibody (ab62401) at 1/0.5 dilution
    Lane 2 : Anti-Caspase-5 antibody (ab62401) at 1/1 dilution
    Lane 3 : Anti-Caspase-5 antibody (ab62401) at 1/2 dilution

    All lanes : Ramos cells

    Predicted band size: 48 kDa

  • Immunocytochemistry image of ab62401 stained P815 cells using 2µg/ml antibody.   
  • Immunofluorescence of Caspase-5 in P815 cells using ab62401 at 2 ug/ml.

References

ab62401 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab62401.
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