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Goat polyclonal to Caspase-6 / CASP-6
ab178540 is expected to recognize both reported isoforms of Caspase-6 / CASP-6 (NP_001217.2; NP_116787.1).
Synthetic peptide corresponding to Human Caspase-6/ CASP-6 aa 181-193 (internal sequence) (Cysteine residue).
Database link: P55212
Previously labelled as Caspase-6.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA
Concentration information loading...
Protein G purified
ab178540 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Belongs to the peptidase C14A family.
Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
Information by UniProt
- Apoptotic protease Mch-2 antibody
- Apoptotic protease MCH2 antibody
- CASP-6 antibody
has not yet been referenced specifically in any publications.
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