Anti-Caspase-6 / CASP-6 antibody (ab178540)

Overview

  • Product name
    Anti-Caspase-6 / CASP-6 antibody
    See all Caspase-6 / CASP-6 primary antibodies
  • Description
    Goat polyclonal to Caspase-6 / CASP-6
  • Host species
    Goat
  • Specificity
    ab178540 is expected to recognize both reported isoforms of Caspase-6 / CASP-6 (NP_001217.2; NP_116787.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Caspase-6/ CASP-6 aa 181-193 (internal sequence) (Cysteine residue).
    Sequence:

    QTEKLDTNITEVD


    Database link: P55212

  • Positive control
    • Human Colon lysate.
  • General notes

    Previously labelled as Caspase-6. 

Properties

Applications

Our Abpromise guarantee covers the use of ab178540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

Target

  • Function
    Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
  • Sequence similarities
    Belongs to the peptidase C14A family.
  • Post-translational
    modifications
    Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptotic protease Mch-2 antibody
    • Apoptotic protease MCH2 antibody
    • CASP-6 antibody
    • CASP6 antibody
    • CASP6_HUMAN antibody
    • Caspase 6 antibody
    • Caspase 6 apoptosis related cysteine protease antibody
    • Caspase 6, apoptosis related cysteine peptidase antibody
    • Caspase-6 antibody
    • Caspase-6 subunit p11 antibody
    • Mch2 antibody
    • OTTHUMP00000162742 antibody
    • OTTHUMP00000162743 antibody
    see all

Images

  • Anti-Caspase-6 / CASP-6 antibody (ab178540) at 0.3 µg/ml + Human Colon lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 33 kDa

References

ab178540 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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