Product nameCaspase-6 / CASP-6 peptide
See all Caspase-6 / CASP-6 proteins and peptides
Amino Acid Sequence
Our Abpromise guarantee covers the use of ab38263 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Previously labelled as Caspase-6.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 0.1% BSA, PBS, pH 7.2
- Apoptotic protease Mch-2
- Apoptotic protease MCH2
FunctionInvolved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
Sequence similaritiesBelongs to the peptidase C14A family.
modificationsCleavages by caspase-3, caspase-8 or -10 generate the two active subunits.
- Information by UniProt
ab38263 has not yet been referenced specifically in any publications.