Recombinant
RabMAb

Recombinant Anti-Caspase-6/CASP-6 antibody [EPR4405] - BSA and Azide free (ab247635)

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Overview

  • Product name

    Anti-Caspase-6/CASP-6 antibody [EPR4405] - BSA and Azide free
    See all Caspase-6/CASP-6 primary antibodies

  • Description

    Rabbit monoclonal [EPR4405] to Caspase-6/CASP-6 - BSA and Azide free

  • Host species

    Rabbit

  • Specificity

    This antibody detects both the full length and cleaved forms of Caspase-6/CASP-6.

  • Tested applications

    Suitable for: Flow Cyt, IP, WBmore details
    Unsuitable for: ICC or IHC-P

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide within Human Caspase-6/CASP-6 aa 150-250. The exact sequence is proprietary.
    Database link: P55212

  • General notes

    Ab247635 is the carrier-free version of ab108335. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab247635 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab247635 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
  • Application notes
    Is unsuitable for ICC or IHC-P.

    • Target

    • Function

      Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

    • Sequence similarities

      Belongs to the peptidase C14A family.

    • Post-translational
      modifications

      Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • Apoptotic protease Mch-2 antibody
      • Apoptotic protease MCH2 antibody
      • CASP-6 antibody
      • CASP6 antibody
      • CASP6_HUMAN antibody
      • Caspase 6 antibody
      • Caspase 6 apoptosis related cysteine protease antibody
      • Caspase 6, apoptosis related cysteine peptidase antibody
      • Caspase-6 antibody
      • Caspase-6 subunit p11 antibody
      • Mch2 antibody
      • OTTHUMP00000162742 antibody
      • OTTHUMP00000162743 antibody
      see all

    References

    ab247635 has not yet been referenced specifically in any publications.

    Publishing research using ab247635? Please let us know so that we can cite the reference in this datasheet.

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