Product nameCaspase Family Colorimetric Substrate Kit II Plus
See all Caspase Family kits
Sample typeAdherent cells, Suspension cells
Assay typeEnzyme activity
Abcam's Caspase Family Colorimetric Substrate Kit II Plus provides ready-to-use colorimetric substrates for members of caspase family proteases. All substrates are provided in liquid ready-to-use form.
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Storage instructionsStore at -20°C. Please refer to protocols.
Components 25 tests 2X Reaction Buffer 1 x 20ml Caspase 6 Substrate, Ac-VEID-PNA 1 x 125µl Caspase-1 Substrate, Ac-YVAD-pNA 1 x 125µl Caspase-10 Substrate, Ac-AEVD-PNA 1 x 125µl Caspase-2 Substrate, Ac-VDVAD-pNA 1 x 125µl Caspase-3 Substrate, Ac-DEVD-pNA 1 x 125µl Caspase-4 Substrate, Ac-LEVD-PNA 1 x 125µl Caspase-5 Substrate, Ac-WEHD-pNA 1 x 125µl Caspase-8 Substrate, Ac-IETD-pNA 1 x 125µl Caspase-9 Substrate, Ac-LEHD-pNA 1 x 125µl Cell Lysis Buffer 1 x 100ml Dilution Buffer 1 x 200ml DTT 1 x 400µl
RelevanceCaspases are members of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
- CASP 2
ab102488 has not yet been referenced specifically in any publications.