Product nameCaspase Family Colorimetric Substrate Kit Plus
See all Caspase Family kits
Sample typeAdherent cells, Suspension cells
Assay typeEnzyme activity
Species reactivityReacts with: Other species, Mammals
Abcam's Caspase Family Colorimetric Substrate Kit Plus provides ready-to-use colorimetric substrates for members of caspase family proteases. All substrates are provided in liquid ready-to-use form.
This kit is the idea tool to test which caspases are activated when apoptosis is induced in a particular cell type.
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Storage instructionsStore at -20°C. Please refer to protocols.
Components 25 tests 2X Reaction Buffer 1 x 20ml Caspase 6 Substrate, Ac-VEID-PNA 1 x 125µl Caspase-1 Substrate, Ac-YVAD-pNA 1 x 125µl Caspase-2 Substrate, Ac-VDVAD-pNA 1 x 125µl Caspase-3 Substrate, Ac-DEVD-pNA 1 x 125µl Caspase-5 Substrate, Ac-WEHD-pNA 1 x 125µl Caspase-8 Substrate, Ac-IETD-pNA 1 x 125µl Caspase-9 Substrate, Ac-LEHD-pNA 1 x 125µl Cell Lysis Buffer 1 x 100ml Dilution Buffer 1 x 160ml DTT 1 x 400µl
RelevanceCaspases are members of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
- CASP 2
ab102486 has not yet been referenced specifically in any publications.