Overview

  • Product name

    Caspofungin acetate, Antifungal agent
  • Description

    Potent antifungal agent. 1,3-beta-D-glucan synthase inhibitor.
  • Biological description

    Potent antifungal agent (MIC values are 13 and 25 nM for C. Albicans and C. Krusei resepectively). 1,3-beta-D-glucan synthase inhibitor. Inhibits β (1,3)-D-glucan biosynthesis. Shows antifungal effects in vivo. Orally active.
  • CAS Number

    179463-17-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zhang M  et al. Efficacy of the combination of voriconazole and caspofungin in experimental pulmonary aspergillosis by different Aspergillus species. Mycopathologia 177:11-8 (2014). Read more (PubMed: 24306184) »
  • Sun P & Tong Z Efficacy of caspofungin, a 1,3-ß-D-glucan synthase inhibitor, on Pneumocystis carinii pneumonia in rats. Med Mycol 52:798-803 (2014). Read more (PubMed: 25288652) »
  • Ibrahim AS  et al. Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis. Antimicrob Agents Chemother 49:721-7 (2005). Read more (PubMed: 15673756) »
See 1 Publication for this product

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