Overview

  • Product name

  • Description

    Rabbit polyclonal to Catalase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Catalase aa 292-320 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    FPFNPFDLTKVWPHKDYPLIPVGKLVLNR


    Database link: P04040

  • Positive control

    • Rat kidney lysate, Rat brain lysate, Mouse liver lysate; Rat kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab217793 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 60 kDa).
IHC-P 1/100 - 1/500.
Flow Cyt 1/50.

Target

  • Function

    Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
  • Involvement in disease

    Defects in CAT are the cause of acatalasia (ACATLAS) [MIM:115500]; also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
  • Sequence similarities

    Belongs to the catalase family.
  • Post-translational
    modifications

    The N-terminus is blocked.
  • Cellular localization

    Peroxisome.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cas1 antibody
    • CAT antibody
    • CATA_HUMAN antibody
    • Catalase antibody
    • Cs1 antibody
    • MGC138422 antibody
    • MGC138424 antibody
    see all

Images

  • Flow Cytometry of HL-60 cells with ab216640 at 1/50
  • Immunohistochemical analysis of formalin fixed, paraffin embedded Rat kidney tissue labeling Catalase with ab217793 at 1/100 dilution followed by conjugation to the secondary antibody and DAB staining.

  • All lanes : Anti-Catalase antibody (ab217793) at 1/200 dilution

    Lane 1 : Rat kidney lysate
    Lane 2 : Rat brain lysate

    Secondary
    All lanes : Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/3000 dilution

    Predicted band size: 60 kDa

  • Anti-Catalase antibody (ab217793) at 1/300 dilution + Mouse liver lysate

    Secondary
    Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/500 dilution

    Predicted band size: 60 kDa

References

ab217793 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab217793.
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