Anti-Cathelicidin/CLP antibody [H7] (ab80895)
Key features and details
- Mouse monoclonal [H7] to Cathelicidin/CLP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
Anti-Cathelicidin/CLP antibody [H7]
See all Cathelicidin/CLP primary antibodies -
Description
Mouse monoclonal [H7] to Cathelicidin/CLP -
Host species
Mouse -
Specificity
This antibody is specific for Human Cathelicidin/CLP 115-NQARGSF-121 in pro domain.
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Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Full length protein. This information is proprietary to Abcam and/or its suppliers.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
H7 -
Myeloma
P3U1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab80895 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa.
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Notes |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa. |
Target
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Function
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. -
Tissue specificity
Expressed in bone marrow and testis and neutrophils. -
Sequence similarities
Belongs to the cathelicidin family. -
Post-translational
modificationsThe N-terminus is blocked. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 820 Human
- Omim: 600474 Human
- SwissProt: P49913 Human
- Unigene: 51120 Human
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Alternative names
- 18 kDa cationic antimicrobial protein antibody
- Antibacterial peptide LL-37 antibody
- Antibacterial protein FALL-39 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab80895 has been referenced in 5 publications.
- Woodby B et al. Cutaneous antimicrobial peptides: New "actors" in pollution related inflammatory conditions. Redox Biol 41:101952 (2021). PubMed: 33839421
- Wang G et al. Cathelicidin antimicrobial peptide (CAMP) gene promoter methylation induces chondrocyte apoptosis. Hum Genomics 15:24 (2021). PubMed: 33892795
- Zhou YQ et al. Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection. EMBO Mol Med 12:e10233 (2020). PubMed: 31782624
- Wang L et al. Hyperglycemia Induces Neutrophil Extracellular Traps Formation Through an NADPH Oxidase-Dependent Pathway in Diabetic Retinopathy. Front Immunol 9:3076 (2018). PubMed: 30671057
- Stie J et al. Localization of hCAP-18 on the surface of chemoattractant-stimulated human granulocytes: analysis using two novel hCAP-18-specific monoclonal antibodies. J Leukoc Biol 82:161-72 (2007). PubMed: 17400609