Overview

  • Product name

    Anti-Cathelicidin/CLP antibody [mAbcam 58387]
    See all Cathelicidin/CLP primary antibodies
  • Description

    Mouse monoclonal [mAbcam 58387] to Cathelicidin/CLP
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human Cathelicidin/CLP aa 150 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab106671)

  • Positive control

    • This antibody gave a positive signal in human spleen tissue lysate.
  • General notes

    This antibody clone is manufactured by Abcam.

     

    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.

    If you require this antibody in a particular buffer formulation or a particular conjugate for your experiments, please contact orders@abcam.com or you can find further information here.

     This product was previously labelled as Cathelicidin

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity

    IgG fraction
  • Primary antibody notes

    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.
  • Clonality

    Monoclonal
  • Clone number

    mAbcam 58387
  • Myeloma

    Sp2/0-Ag14
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab58387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 10 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).

Target

  • Function

    Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
  • Tissue specificity

    Expressed in bone marrow and testis and neutrophils.
  • Sequence similarities

    Belongs to the cathelicidin family.
  • Post-translational
    modifications

    The N-terminus is blocked.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • 18 kDa cationic antimicrobial protein antibody
    • Antibacterial peptide LL-37 antibody
    • Antibacterial protein FALL-39 antibody
    • CAMP antibody
    • CAMP_HUMAN antibody
    • CAP 18 antibody
    • CAP-18 antibody
    • CAP18 antibody
    • Cathelicidin antimicrobial peptide antibody
    • Cathelin-like protein antibody
    • Cathelin-related antimicrobial peptide antibody
    • CATHL3 antibody
    • Cationic antimicrobial protein, 18-KD antibody
    • CLP antibody
    • Cnlp antibody
    • Cramp antibody
    • CRAMP, mouse, homolog of antibody
    • FALL 39 antibody
    • FALL-39 peptide antibiotic antibody
    • FALL39 antibody
    • hCAP 18 antibody
    • hCAP-18 antibody
    • hCAP18 antibody
    • HSD26 antibody
    • LL37 antibody
    • MCLP antibody
    • Peptide antibiotic, PR-39, porcine, homolog of antibody
    see all

Images

  • Anti-Cathelicidin/CLP antibody [mAbcam 58387] (ab58387) at 10 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 20 µg

    Secondary
    Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 19 kDa
    Observed band size: 19 kDa
    Additional bands at: 60 kDa. We are unsure as to the identity of these extra bands.


    Exposure time: 30 seconds

References

This product has been referenced in:

  • Zhang X  et al. Identification and Validation of a Salivary Protein Panel to Detect Heart Failure Early. Theranostics 7:4350-4358 (2017). Read more (PubMed: 29158831) »
See 1 Publication for this product

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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