Product nameAnti-Cathepsin B antibody
See all Cathepsin B primary antibodies
DescriptionRabbit polyclonal to Cathepsin B
Tested applicationsSuitable for: ELISA, WB, ICC/IF, IPmore details
Species reactivityReacts with: Human
Full length native protein (purified): Cathepsin B from Human liver.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration information loading...
Our Abpromise guarantee covers the use of ab30443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||1/250 - 1/500.|
|WB||1/1000 - 1/5000. Predicted molecular weight: 38 kDa.|
|ICC/IF||Use at an assay dependent concentration. See Abreview.|
|IP||Use at an assay dependent concentration. PubMed: 24833013|
FunctionThiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Sequence similaritiesBelongs to the peptidase C1 family.
Cellular localizationLysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- Information by UniProt
- Amyloid precursor protein secretase antibody
- APP secretase antibody
- APPS antibody
This product has been referenced in:
- Han X et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell 15:416-27 (2016). Read more (PubMed: 26890602) »
- Lohoefer F et al. Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Exp Mol Med 46:e95 (2014). WB, IP ; Human . Read more (PubMed: 24833013) »