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ab58802 has been referenced in 35 publications.

  • Li G & Moellering RE A Concise, Modular Antibody-Oligonucleotide Conjugation Strategy Based on Disuccinimidyl Ester Activation Chemistry. Chembiochem N/A:N/A (2019). PubMed: 30767357
  • Chen CH  et al. Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts. Oncogenesis 8:15 (2019). PubMed: 30796200
  • Tang Y  et al. Cathepsin B inhibition ameliorates the non-alcoholic steatohepatitis through suppressing caspase-1 activation. J Physiol Biochem N/A:N/A (2018). PubMed: 30019185
  • Hsu SPC  et al. Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells. Oncotarget 9:6883-6896 (2018). PubMed: 29467937
  • Komura T  et al. Clinical features of cystatin A expression in patients with pancreatic ductal adenocarcinoma. Cancer Sci 108:2122-2129 (2017). IHC ; Human . PubMed: 28898495
  • Manchanda M  et al. Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models. Clin Transl Gastroenterol 8:e99 (2017). IHC-P . PubMed: 28617446
  • Mizunoe Y  et al. Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. Autophagy 13:642-653 (2017). PubMed: 28121218
  • Li G  et al. An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Nat Commun 8:1775 (2017). PubMed: 29176560
  • Zhang S  et al. Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal. J Neurochem 140:941-954 (2017). PubMed: 28095639
  • Cui D  et al. Impaired autophagosome clearance contributes to neuronal death in a piglet model of neonatal hypoxic-ischemic encephalopathy. Cell Death Dis 8:e2919 (2017). WB . PubMed: 28703794
  • Tsubone TM  et al. Enhanced efficiency of cell death by lysosome-specific photodamage. Sci Rep 7:6734 (2017). ICC/IF ; Human . PubMed: 28751688
  • Fernandez-Fernandez MR  et al. 3D electron tomography of brain tissue unveils distinct Golgi structures that sequester cytoplasmic contents in neurons. J Cell Sci 130:83-89 (2017). PubMed: 27505890
  • Ben-Aderet L  et al. Detecting cathepsin activity in human osteoarthritis via activity-based probes. Arthritis Res Ther 17:69 (2015). WB . PubMed: 25889265
  • Aboelenain M  et al. Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle. J Reprod Dev 61:229-36 (2015). IHC . PubMed: 25819401
  • Liu WJ  et al. Autophagy-Lysosome Pathway in Renal Tubular Epithelial Cells Is Disrupted by Advanced Glycation End Products in Diabetic Nephropathy. J Biol Chem 290:20499-510 (2015). PubMed: 26100632
  • Kim SH  et al. Inhibition of cathepsin B activity reduces apoptosis by preventing cytochrome c release from mitochondria in porcine parthenotes. J Reprod Dev 61:261-8 (2015). IF . PubMed: 25903788
  • O'Donovan TR  et al. Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo. PLoS One 10:e0134676 (2015). PubMed: 26248051
  • Wu QQ  et al. Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-a/ASK1/JNK pathway. Am J Physiol Heart Circ Physiol 308:H1143-54 (2015). PubMed: 25713304
  • Cheng YL  et al. Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1ß production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation. Immunology 145:258-67 (2015). ICC/IF ; Mouse, Human . PubMed: 25580516
  • Guo B  et al. The nascent polypeptide-associated complex is essential for autophagic flux. Autophagy 10:1738-48 (2014). PubMed: 25126725
  • Hibbert B  et al. Glycogen synthase kinase-3ß inhibition augments diabetic endothelial progenitor cell abundance and functionality via cathepsin B: a novel therapeutic opportunity for arterial repair. Diabetes 63:1410-21 (2014). WB ; Human . PubMed: 24296714
  • Porter KM  et al. MTOR-independent induction of autophagy in trabecular meshwork cells subjected to biaxial stretch. Biochim Biophys Acta 1843:1054-62 (2014). PubMed: 24583119
  • Granato M  et al. Hepatitis C virus present in the sera of infected patients interferes with the autophagic process of monocytes impairing their in-vitro differentiation into dendritic cells. Biochim Biophys Acta 1843:1348-55 (2014). PubMed: 24726834
  • Porter K  et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy 9:581-94 (2013). PubMed: 23360789
  • Shimizu A  et al. Netrin-1 Promotes Glioblastoma Cell Invasiveness and Angiogenesis by Multiple Pathways Including Activation of RhoA, Cathepsin B, and cAMP-response Element-binding Protein. J Biol Chem 288:2210-22 (2013). ICC/IF ; Human . PubMed: 23195957
  • Porter K  et al. Cathepsin B is up-regulated and mediates extracellular matrix degradation in trabecular meshwork cells following phagocytic challenge. PLoS One 8:e68668 (2013). WB . PubMed: 23844232
  • Balboula AZ  et al. Cathepsin B activity has a crucial role in the developmental competence of bovine cumulus-oocyte complexes exposed to heat shock during in vitro maturation. Reproduction 146:407-17 (2013). PubMed: 23898216
  • Owa C  et al. Triptolide induces lysosomal-mediated programmed cell death in MCF-7 breast cancer cells. Int J Womens Health 5:557-69 (2013). WB . PubMed: 24043955
  • Li S  et al. Cathepsin B Contributes to Autophagy-related 7 (Atg7)-induced Nod-like Receptor 3 (NLRP3)-dependent Proinflammatory Response and Aggravates Lipotoxicity in Rat Insulinoma Cell Line. J Biol Chem 288:30094-104 (2013). WB ; Rat . PubMed: 23986436
  • Wang F  et al. The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes. Nanomedicine 9:1159-68 (2013). WB . PubMed: 23660460
  • Abdallah AM  et al. Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation. J Immunol 187:4744-53 (2011). WB . PubMed: 21957139
  • Meixenberger K  et al. Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol 184:922-30 (2010). ICC/IF ; Human, Mouse . PubMed: 20008285
  • Garrido-Gomez T  et al. Modeling Human Endometrial Decidualization from the Interaction between Proteome and Secretome. J Clin Endocrinol Metab : (2010). WB ; Human . PubMed: 21190976
  • Lin Y  et al. Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress. Invest Ophthalmol Vis Sci 51:6483-95 (2010). WB . PubMed: 20574010
  • Lawlor K  et al. Pathway-based biomarker search by high-throughput proteomics profiling of secretomes. J Proteome Res 8:1489-503 (2009). PubMed: 19199430

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