Recombinant
RabMAb

Recombinant Anti-Cathepsin D antibody [EPR3056Y] - BSA and Azide free (ab207550)

Overview

  • Product name

    Anti-Cathepsin D antibody [EPR3056Y] - BSA and Azide free
    See all Cathepsin D primary antibodies
  • Description

    Rabbit monoclonal [EPR3056Y] to Cathepsin D - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, ICC, IHC-P, WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Cathepsin D aa 50-150 (N terminal).

  • Positive control

    • MCF-7 and SKBR3 cell lysates. Human liver tissue.
  • General notes

    Ab207550 is the carrier-free version of ab75811. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab207550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
    • Tissue specificity

      Expressed in the aorta extrcellular space (at protein level).
    • Involvement in disease

      Ceroid lipofuscinosis, neuronal, 10
    • Sequence similarities

      Belongs to the peptidase A1 family.
      Contains 1 peptidase A1 domain.
    • Post-translational
      modifications

      N- and O-glycosylated.
    • Cellular localization

      Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
    • Information by UniProt
    • Database links

    • Alternative names

      • CatD antibody
      • CATD_HUMAN antibody
      • Cathepsin D antibody
      • Cathepsin D heavy chain antibody
      • CD antibody
      • Ceroid lipofuscinosis neuronal 10 antibody
      • CLN10 antibody
      • CPSD antibody
      • ctsd antibody
      • Epididymis secretory sperm binding protein Li 130P antibody
      • HEL S 130P antibody
      • Lysosomal aspartyl peptidase antibody
      • Lysosomal aspartyl protease antibody
      • MGC2311 antibody
      see all

    References

    ab207550 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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