Anti-Cathepsin G antibody (ab131407)
Key features and details
- Rabbit polyclonal to Cathepsin G
- Suitable for: ELISA, ICC, IP, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Cathepsin G antibody
See all Cathepsin G primary antibodies -
Description
Rabbit polyclonal to Cathepsin G -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, ICC, IP, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Purified Human Cathepsin G.
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General notes
Variations in temperature due to freeze-thaw cycles may cause loss of activity when rehydrated product is stored in aliquots of less than 50µl.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, 49% Water -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab131407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain. -
Cellular localization
Cell surface. - Information by UniProt
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Database links
- Entrez Gene: 1511 Human
- Omim: 116830 Human
- SwissProt: P08311 Human
- Unigene: 421724 Human
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Alternative names
- CATG antibody
- CATG_HUMAN antibody
- Cathepsin G antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab131407 has been referenced in 3 publications.
- Kasperkiewicz P et al. NETosis occurs independently of neutrophil serine proteases. J Biol Chem 295:17624-17631 (2020). PubMed: 33454002
- Stopa JD et al. Kinetic-based trapping by intervening sequence variants of the active sites of protein-disulfide isomerase identifies platelet protein substrates. J Biol Chem 292:9063-9074 (2017). PubMed: 28364042
- Kasperkiewicz P et al. Toolbox of Fluorescent Probes for Parallel Imaging Reveals Uneven Location of Serine Proteases in Neutrophils. J Am Chem Soc 139:10115-10125 (2017). PubMed: 28672107