Product nameCathepsin K peptide
See all Cathepsin K proteins and peptides
Our Abpromise guarantee covers the use of ab41720 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Cathepsin K antibody (ab19027)
Purity> 95 % SDS-PAGE.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 0.1% BSA, PBS, pH 7.2
- Cathepsin K
- Cathepsin O
- Cathepsin O1
FunctionClosely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
Tissue specificityPredominantly expressed in osteclasts (bones).
Involvement in diseaseDefects in CTSK are the cause of pycnodysostosis (PKND) [MIM:265800]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.
Sequence similaritiesBelongs to the peptidase C1 family.
- Information by UniProt
ab41720 has not yet been referenced specifically in any publications.