Anti-Cathepsin S antibody (ab232740)
Key features and details
- Rabbit polyclonal to Cathepsin S
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Pig
- Isotype: IgG
Overview
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Product name
Anti-Cathepsin S antibody
See all Cathepsin S primary antibodies -
Description
Rabbit polyclonal to Cathepsin S -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Pig
Predicted to work with: Cow, Dog -
Immunogen
Recombinant fragment (His-T7-tag) corresponding to Cow Cathepsin S aa 100 to the C-terminus. Expressed in E.coli.
Database link: P25326 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab232740 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 37 kDa.
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Notes |
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IHC-P
Use at an assay dependent concentration. |
WB
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 37 kDa. |
Target
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Function
Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. -
Sequence similarities
Belongs to the peptidase C1 family. -
Cellular localization
Lysosome. - Information by UniProt
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Database links
- Entrez Gene: 327711 Cow
- Entrez Gene: 403400 Dog
- Entrez Gene: 13040 Mouse
- SwissProt: P25326 Cow
- SwissProt: Q8HY81 Dog
- SwissProt: O70370 Mouse
- Unigene: 3619 Mouse
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Alternative names
- Cathepsin S antibody
- CathepsinS antibody
- CATS_HUMAN antibody
- Ctss antibody
Images
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Anti-Cathepsin S antibody (ab232740) at 2 µg/ml + Recombinant cow Cathepsin S protein.
Predicted band size: 37 kDa -
Anti-Cathepsin S antibody (ab232740) at 2 µg/ml + Mouse liver lysate.
Developed using the ECL technique.
Predicted band size: 37 kDa -
Anti-Cathepsin S antibody (ab232740) at 1 µg/ml + Pig spleen tissue lysate.
Developed using the ECL technique.
Predicted band size: 37 kDa
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab232740 has been referenced in 2 publications.
- Peng K et al. Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis. J Cell Physiol 236:1309-1320 (2021). PubMed: 32657442
- Bratovš A et al. Stefin A-functionalized liposomes as a system for cathepsins S and L-targeted drug delivery. Biochimie 166:94-102 (2019). PubMed: 31163196