CAY10429 (Abn-cbd), endocannabinoid receptor ligand (ab144464)

Overview

  • Product name

    CAY10429 (Abn-cbd), endocannabinoid receptor ligand
  • Description

    Non-CB1/CB2 endocannabinoid receptor ligand
  • Alternative names

    • Abn-cbd
  • Biological description

    Non-CB1/CB2 endocannabinoid receptor ligand. Neurobehaviorally inactive cannabinoid. Regulates the migratory activity of murine BV-2 microglial cells (EC50 = 600 nM). Induces endothelium-independent vasodilation. Shows hypotensive effects in vivo.
  • Purity

    > 98%
  • CAS Number

    22972-55-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
  • Molecular weight

    314.50
  • Molecular formula

    C21H30O2
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Su EN  et al. Role of Endothelium in Abnormal Cannabidiol-Induced Vasoactivity in Retinal Arterioles. Invest Ophthalmol Vis Sci 56:4029-37 (2015). Read more (PubMed: 26098470) »
  • Walter L  et al. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. J Neurosci 23:1398-405 (2003). Read more (PubMed: 12598628) »
  • Járai Z  et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A 96:14136-41 (1999). Read more (PubMed: 10570211) »

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